---
title: Evidence-based Wellness Education
description: Evidence-based nutrition science, peer-reviewed and free for everyone. An educational publication of Designs for Health.
---

An **educational publication of Designs for Health**

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# The CASI Library

 Peer-reviewed nutrition science, organized by topic and section.

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## Recent articles

### [![A Case Series on an Allulose-Containing Gummy in Healthy Adults Monitored by Continuous Glucose Monitoring](https://www.casi.org/hs-fs/hubfs/Sept-CASI-Allulose%20%281%29.jpeg?width=960) Science Update A Case Series on an Allulose-Containing Gummy in Healthy Adults Monitored by Continuous Glucose Monitoring Explore a CGM-monitored case series on how an allulose gummy may help reduce postprandial glucose spikes and glycemic variability in healthy adults. Sep 09, 2026 Read →](https://www.casi.org/articles/a-case-series-on-an-allulose-containing-gummy-in-healthy-adults-monitored-by-continuous-glucose-monitoring)

### [![A Case Report on Vitamin C Supplementation in a 67-Year-Old Male with Leukopenia](https://www.casi.org/hs-fs/hubfs/July-21_Leukopenia-vita-c_460547506.jpeg?width=960) Science Update A Case Report on Vitamin C Supplementation in a 67-Year-Old Male with Leukopenia Explore a case report on oral vitamin C supplementation and changes in white blood cell and neutrophil counts in a 67-year-old man with chronic leukopenia. Jul 21, 2026 Read →](https://www.casi.org/articles/a-case-report-on-vitamin-c-supplementation-in-a-67-year-old-male-with-leukopenia)

### [![Hydrolyzed Whey Protein for Athletes: Enhanced Digestibility, Absorption, and Recovery](https://www.casi.org/hs-fs/hubfs/June-30-Hydrolyzed-Whey-Protein-for-Athletes.jpeg?width=960) Research & Education Hydrolyzed Whey Protein for Athletes: Enhanced Digestibility, Absorption, and Recovery Discover the benefits of hydrolyzed whey protein for athletes, including faster absorption, easier digestion, muscle growth, and post-workout recovery. Jun 30, 2026 Read →](https://www.casi.org/articles/hydrolyzed-whey-protein-for-athletes-enhanced-digestibility-absorption-and-recovery)

### [![B Vitamins 101: Functions, Food Sources, and Daily Requirements](https://www.casi.org/hs-fs/hubfs/June-25-B-Vitamins-101.jpeg?width=960) Research & Education B Vitamins 101: Functions, Food Sources, and Daily Requirements Explore all eight B vitamins, their functions, best food sources, daily requirements, deficiency risks, and preferred supplement forms for optimal health. Jun 25, 2026 Read →](https://www.casi.org/articles/b-vitamins-101-functions-food-sources-and-daily-requirements)

### [![A Clinical Trial on Geranylgeraniol Supplementation for Testosterone Support in Middle-Aged Adults](https://www.casi.org/hs-fs/hubfs/casi/archive/june16-gg-testosterone.jpg?width=960) Science Update A Clinical Trial on Geranylgeraniol Supplementation for Testosterone Support in Middle-Aged Adults Geranylgeraniol did not raise testosterone overall, but a trial found men with lower baseline levels saw about a 28 ng/dL increase after supplementation. Jun 17, 2026 Read →](https://www.casi.org/articles/geranylgeraniol-supplementation-testosterone-support)

### [![PCOS Is Now PMOS: Understanding the New Terminology and Its Metabolic Implications](https://www.casi.org/hs-fs/hubfs/June-11-PCOS-is-Now-PMOS.jpeg?width=960) Research & Education PCOS Is Now PMOS: Understanding the New Terminology and Its Metabolic Implications PCOS is now PMOS. Learn what polyendocrine metabolic ovarian syndrome means and how insulin resistance influences symptoms and long-term metabolic health. Jun 11, 2026 Read →](https://www.casi.org/articles/pcos-is-now-pmos-understanding-the-new-terminology-and-its-metabolic-implications)

### [![Magnesium Supplementation 101: Choosing the Best Form for Your Patient’s Needs](https://www.casi.org/hs-fs/hubfs/June-2-Magnesium-Supplementation-101.jpeg?width=960) Research & Education Magnesium Supplementation 101: Choosing the Best Form for Your Patient’s Needs Compare types of magnesium supplements, including glycinate, malate, L-threonate, and citrate, to choose the best form for sleep, energy, and digestion. Jun 02, 2026 Read →](https://www.casi.org/articles/magnesium-supplementation-101-choosing-the-best-form-for-your-patients-needs)

### [![How Akkermansia Supports GLP-1 Production and Metabolic Function](https://www.casi.org/hs-fs/hubfs/casi/archive/may-26-akkermansia-glp-1.jpg?width=960) Research & Education How Akkermansia Supports GLP-1 Production and Metabolic Function Akkermansia muciniphila, a keystone gut bacterium, appears to support the body's own GLP-1 production through short-chain fatty acids and the P9 protein. May 27, 2026 Read →](https://www.casi.org/articles/akkermansia-supports-glp-1-production-metabolic-function)

### [![Magnesium Glycinate Chelate Buffered: A Smart Approach to Magnesium Supplementation](https://www.casi.org/hs-fs/hubfs/May-21-%20Magnesium-Glycinate-Chelate-Buffered%20%281%29.jpeg?width=960) Research & Education Magnesium Glycinate Chelate Buffered: A Smart Approach to Magnesium Supplementation Discover how buffered magnesium glycinate combines chelated magnesium and magnesium oxide to support absorption, bioavailability, and digestive comfort. May 21, 2026 Read →](https://www.casi.org/articles/magnesium-glycinate-chelate-buffered-a-smart-approach-to-magnesium-supplementation)

### [![Overcoming the Anaerobic Barrier: A New Approach to Probiotic Manufacturing](https://www.casi.org/hs-fs/hubfs/May-12-Overcoming-the-Anaerobic-Barrier.jpeg?width=960) Research & Education Overcoming the Anaerobic Barrier: A New Approach to Probiotic Manufacturing Learn how anaerobic probiotic manufacturing and MET technology enable shelf-stable, next-generation probiotics with oxygen-sensitive keystone gut bacteria. May 12, 2026 Read →](https://www.casi.org/articles/overcoming-the-anaerobic-barrier-a-new-approach-to-probiotic-manufacturing)

### [![A Case Report on a Functional GI Testing Protocol in a 35-Year-Old Female with Gastrointestinal and Joint Discomfort](https://www.casi.org/hs-fs/hubfs/May-7-Functional-GI-Testing-35-Yr-Old.jpeg?width=960) Science Update A Case Report on a Functional GI Testing Protocol in a 35-Year-Old Female with Gastrointestinal and Joint Discomfort Explore how functional GI testing and comprehensive stool analysis guided a personalized protocol for gastrointestinal symptoms and joint discomfort. May 07, 2026 Read →](https://www.casi.org/articles/a-case-report-on-a-functional-gi-testing-protocol-in-a-35-year-old-female-with-gastrointestinal-and-joint-discomfort)

### [![Beyond Standard Labs: How Functional Testing Enhances Clinical Insight](https://www.casi.org/hs-fs/hubfs/Image%209-14-26%20at%202.53%20PM.png?width=960) Research & Education Beyond Standard Labs: How Functional Testing Enhances Clinical Insight Discover how functional testing complements standard tests to uncover root causes, analyze health patterns, and guide care for persistent symptoms. Apr 29, 2026 Read →](https://www.casi.org/articles/functional-testing-clinical-insight)

### [![Integrative Management of Estrogen Dominance, Methylation Impairment, and Histamine Intolerance in Perimenopause: A Case Report](https://www.casi.org/hs-fs/hubfs/April-23-Integrative-Management-Estrogen.jpeg?width=960) Science Update Integrative Management of Estrogen Dominance, Methylation Impairment, and Histamine Intolerance in Perimenopause: A Case Report Explore a case report on estrogen dominance in perimenopause, impaired methylation, histamine intolerance, and a personalized integrative health care plan. Apr 23, 2026 Read →](https://www.casi.org/articles/integrative-management-of-estrogen-dominance-methylation-impairment-and-histamine-intolerance-in-perimenopause-a-case-report)

### [![A Case Report on Anaerostipes caccae Supplementation in a 47-Year-Old Female with Long-Term Food Intolerances](https://www.casi.org/hs-fs/hubfs/April-9-Anaerostipes-47-yo-Woman.jpeg?width=960) Science Update A Case Report on Anaerostipes caccae Supplementation in a 47-Year-Old Female with Long-Term Food Intolerances Explore one case report on Anaerostipes caccae, a butyrate-producing probiotic, gut microbiome changes, digestive comfort, and long-term food intolerances. Apr 09, 2026 Read →](https://www.casi.org/articles/a-case-report-on-anaerostipes-caccae-supplementation-in-a-47-year-old-female-with-long-term-food-intolerances)

### [![A Case Report on DIM Supplementation in a 78-Year-Old Male with Elevated Prostate-Specific Antigen (PSA)](https://www.casi.org/hs-fs/hubfs/March-24-DIM-Supplementation.jpeg?width=960) Science Update A Case Report on DIM Supplementation in a 78-Year-Old Male with Elevated Prostate-Specific Antigen (PSA) DIM supplementation and stopping a cholesterol supplement were linked to a sharp PSA drop and rising testosterone in a 78-year-old man's case report. Mar 30, 2026 Read →](https://www.casi.org/articles/dim-supplementation-prostate-specific-antigen)

### [![A Case Report on a Homocysteine-Supporting Nutraceutical in Seven Patients with Elevated Homocysteine](https://www.casi.org/hs-fs/hubfs/casi/featured/march-19-homocysteine.jpeg?width=960) Science Update A Case Report on a Homocysteine-Supporting Nutraceutical in Seven Patients with Elevated Homocysteine A homocysteine-targeted nutraceutical with B vitamins and TMG lowered homocysteine in seven patients, with reductions from 9.4% to 46.4%. Mar 23, 2026 Read →](https://www.casi.org/articles/homocysteine-supporting-nutraceutical)

### [![Ubiquinone vs. Ubiquinol: Does the Form of CoQ10 Matter – Or Is Delivery the Real Key?](https://www.casi.org/hs-fs/hubfs/casi/archive/adobestock_1328538224_1-1.jpg?width=960) Research & Education Ubiquinone vs. Ubiquinol: Does the Form of CoQ10 Matter – Or Is Delivery the Real Key? CoQ10 readily converts between ubiquinone and ubiquinol, and evidence suggests formulation and delivery system may matter more than which form is taken. Mar 17, 2026 Read →](https://www.casi.org/articles/ubiquinone-ubiquinol-coq10-delivery)

### [![Lactium®: A Milk-Derived Bioactive Peptide for Supporting Stress Resilience and Emotional Well-Being](https://www.casi.org/hs-fs/hubfs/casi/featured/march-10-lactium.jpeg?width=960) Research & Education Lactium®: A Milk-Derived Bioactive Peptide for Supporting Stress Resilience and Emotional Well-Being Lactium, a milk-derived peptide containing alpha-casozepine, may support healthy cortisol levels, reduced perceived stress, and better sleep quality. Mar 10, 2026 Read →](https://www.casi.org/articles/lactium-bioactive-peptide-stress-resilience)

### [![Allulose: A Rare Sugar That Supports Postprandial Glycemic Control and Metabolic Flexibility](https://www.casi.org/hs-fs/hubfs/casi/featured/march-5-allulose-rare-sugar.jpeg?width=960) Research & Education Allulose: A Rare Sugar That Supports Postprandial Glycemic Control and Metabolic Flexibility Allulose, a rare sugar with about 70 percent of sucrose's sweetness and minimal calories, blunted postprandial glucose and insulin spikes in trials. Mar 05, 2026 Read →](https://www.casi.org/articles/allulose-postprandial-glycemic-control-metabolic-flexibility)

### [![A Case Report on Nutraceutical Support and Urinary Metabolite Testing on a 61-Year-Old Woman with Menopausal Challenges](https://www.casi.org/hs-fs/hubfs/casi/featured/feb-26-nutraceutical-support-menopausal-challenges.jpeg?width=960) Science Update A Case Report on Nutraceutical Support and Urinary Metabolite Testing on a 61-Year-Old Woman with Menopausal Challenges A 61-year-old postmenopausal woman's urine hormone testing guided a nutraceutical and diet protocol that raised metabolites and eased hot flashes. Feb 27, 2026 Read →](https://www.casi.org/articles/nutraceutical-support-urinary-metabolite-testing)

### [![Sleep Support Beyond Melatonin: Targeting the Gut–Brain Axis with L. gasseri CP2305](https://www.casi.org/hs-fs/hubfs/casi/featured/feb-24-sleep-support-beyond-melatonin.jpeg?width=960) Research & Education Sleep Support Beyond Melatonin: Targeting the Gut–Brain Axis with L. gasseri CP2305 Lactobacillus gasseri CP2305, a heat-treated postbiotic, may support sleep quality and autonomic balance through gut-brain axis signaling, trials show. Feb 23, 2026 Read →](https://www.casi.org/articles/sleep-support-gut-brain-axis-l-gasseri-cp2305)

### [![A Case Report on a Personalized Nutraceutical, Dietary, Lifestyle Protocol Supporting an 11-Year-Old Boy with Crohn’s Disease](https://www.casi.org/hs-fs/hubfs/casi/featured/feb-19-11-yr-old-boy-crohns.jpeg?width=960) Science Update A Case Report on a Personalized Nutraceutical, Dietary, Lifestyle Protocol Supporting an 11-Year-Old Boy with Crohn’s Disease A personalized nutraceutical and dietary protocol in an 11-year-old with Crohn's disease resolved symptoms and normalized fecal calprotectin. Feb 19, 2026 Read →](https://www.casi.org/articles/case-report-protocol-crohns-disease)

### [![The New Way to Support Gut Health: Keystone Commensal Probiotics](https://www.casi.org/hs-fs/hubfs/casi/featured/feb-12-new-way-support-gut-health.jpeg?width=960) Research & Education The New Way to Support Gut Health: Keystone Commensal Probiotics Keystone commensal bacteria support gut microbial stability, and their depletion may explain why probiotics help some but not others. Feb 18, 2026 Read →](https://www.casi.org/articles/support-gut-health-keystone-commensal-probiotics)

### [![Para-Psychobiotics: How Heat-Treated L. gasseri CP2305 Supports Healthy Stress Resilience](https://www.casi.org/hs-fs/hubfs/casi/featured/feb-17-para-psychobiotics.jpeg?width=960) Research & Education Para-Psychobiotics: How Heat-Treated L. gasseri CP2305 Supports Healthy Stress Resilience Heat-treated Lactobacillus gasseri CP2305, a para-psychobiotic, shows in clinical trials that it stabilizes stress markers and supports gut bacteria. Feb 17, 2026 Read →](https://www.casi.org/articles/para-psychobiotics-healthy-stress-resilience)

### [![Your CoQ10 Supplements May be Missing a Key Ingredient: Geranylgeraniol (GG)](https://www.casi.org/hs-fs/hubfs/casi/featured/feb-10-your-c0q10-supplements.jpeg?width=960) Research & Education Your CoQ10 Supplements May be Missing a Key Ingredient: Geranylgeraniol (GG) Geranylgeraniol, an upstream precursor in CoQ10 synthesis, may help restore mitochondrial function that CoQ10 supplementation alone leaves incomplete. Feb 10, 2026 Read →](https://www.casi.org/articles/coq10-supplements-key-ingredient-geranylgeraniol)

### [![Not All Probiotics Are Created Equal](https://www.casi.org/hs-fs/hubfs/casi/featured/feb-3-not-all-probiotics.jpeg?width=960) Research & Education Not All Probiotics Are Created Equal Cross-feeding among keystone gut bacteria like Akkermansia and Bifidobacterium species sustains microbiome stability and butyrate production. Feb 03, 2026 Read →](https://www.casi.org/articles/not-all-probiotics-are-created-equal)

### [![How Intestinal Permeability Impacts Inflammatory Responses and Cardiovascular Health](https://www.casi.org/hs-fs/hubfs/casi/featured/jan-29-intestinal-permeability.jpeg?width=960) Research & Education How Intestinal Permeability Impacts Inflammatory Responses and Cardiovascular Health Intestinal permeability lets microbial products like LPS enter circulation, driving inflammation linked to cardiovascular disease risk. Jan 29, 2026 Read →](https://www.casi.org/articles/intestinal-permeability-inflammatory-responses-cardiovascular-health)

### [![The Gut Ecosystem: Why Biodiversity Matters](https://www.casi.org/hs-fs/hubfs/casi/featured/jan-20-microbiome-diversity.jpeg?width=960) Research & Education The Gut Ecosystem: Why Biodiversity Matters Keystone gut bacteria like Faecalibacterium prausnitzii and Akkermansia muciniphila help sustain microbial diversity and gut ecosystem stability. Jan 20, 2026 Read →](https://www.casi.org/articles/gut-ecosystem-why-biodiversity-matters)

### [![Mitochondrial Health and Cardiovascular Function: The Overlooked Connection](https://www.casi.org/hs-fs/hubfs/casi/featured/jan-15-mitochondrial-health-and-cardiovascular.jpeg?width=960) Research & Education Mitochondrial Health and Cardiovascular Function: The Overlooked Connection Mitochondrial function shapes cardiac energy production, and nutrients like CoQ10, L-carnitine, magnesium, and NAD+ precursors may support heart health. Jan 15, 2026 Read →](https://www.casi.org/articles/mitochondrial-health-cardiovascular-function-connection)

### [![Investigating Collagen Peptides Supplementation on Appetite and GLP-1 Status: A Randomized Controlled Trial](https://www.casi.org/hs-fs/hubfs/casi/featured/jan-6-investigating-collagen-peptides.jpeg?width=960) Science Update Investigating Collagen Peptides Supplementation on Appetite and GLP-1 Status: A Randomized Controlled Trial Collagen peptide supplementation modestly reduced post-exercise energy intake in a trial, alongside higher GLP-1 and insulin and lower ghrelin and leptin. Jan 07, 2026 Read →](https://www.casi.org/articles/collagen-peptides-supplementation-glp-1-status)

### [![Methylation 101: What Is It and Why Does It Matter for Health?](https://www.casi.org/hs-fs/hubfs/casi/archive/dec-23-methylation-101.jpg?width=960) Research & Education Methylation 101: What Is It and Why Does It Matter for Health? Methylation relies on a coordinated network of B vitamins beyond B12 and MTHFR; synergistic B-complex support may help balance homocysteine metabolism. Dec 22, 2025 Read →](https://www.casi.org/articles/methylation-101-what-is-it-and-why-does-it-matter-for-health)

### [![What Makes a Good Multivitamin? A Practical Quality Checklist](https://www.casi.org/hs-fs/hubfs/casi/archive/dec-18-what-makes-a-good-multivitamin.jpg?width=960) Research & Education What Makes a Good Multivitamin? A Practical Quality Checklist Bioavailable vitamin forms, chelated minerals, and third-party testing distinguish high-quality multivitamins from lower-quality formulas. Dec 18, 2025 Read →](https://www.casi.org/articles/what-makes-a-good-multivitamin-a-practical-quality-checklist)

### [![Why Adequate Protein Is Essential in Any Detox Plan](https://www.casi.org/hs-fs/hubfs/casi/featured/dec-9-adequate-protein_1.jpeg?width=960) Research & Education Why Adequate Protein Is Essential in Any Detox Plan Protein supplies amino acids, including cysteine and glycine, that liver Phase II detoxification needs, so detox protocols call for intakes above the RDA. Dec 09, 2025 Read →](https://www.casi.org/articles/why-adequate-protein-essential-detox-plan)

### [![Fiber 101: What It Is, How Much You Need, and Where to Get It](https://www.casi.org/hs-fs/hubfs/casi/featured/nov-25-fiber-101.jpeg?width=960) Research & Education Fiber 101: What It Is, How Much You Need, and Where to Get It Dietary fiber comes in soluble and insoluble forms that support cholesterol, blood sugar, and gut health, though most adults fall short of daily targets. Nov 25, 2025 Read →](https://www.casi.org/articles/fiber-101)

### [![From Source to Scoop: How to Choose High-Quality Protein Powders](https://www.casi.org/hs-fs/hubfs/casi/featured/nov-20-from-source-to-scoop-protein-powder.jpeg?width=960) Research & Education From Source to Scoop: How to Choose High-Quality Protein Powders Independent testing found lead and other heavy metals in many commercial protein powders, and outlines third-party certifications that verify purity. Nov 20, 2025 Read →](https://www.casi.org/articles/how-to-choose-high-quality-protein-powders)

### [![Gut and Immune Health: A Clinical Review of Their Interconnected Systems](https://www.casi.org/hs-fs/hubfs/casi/featured/nov-11-gut-and-immune-health.jpeg?width=960) Research & Education Gut and Immune Health: A Clinical Review of Their Interconnected Systems The gut microbiome shapes immune health through short-chain fatty acids and lymphoid tissue, and fiber-rich diets are linked to lower inflammation. Nov 12, 2025 Read →](https://www.casi.org/articles/gut-immune-health-interconnected-systems)

### [![What Are Keystone Probiotic Species?](https://www.casi.org/hs-fs/hubfs/casi/featured/oct-30-key-to-gut-harmony.jpeg?width=960) Research & Education What Are Keystone Probiotic Species? The HACK index ranks over 200 gut bacterial taxa by stability and health association, identifying keystone species beyond common probiotics. Oct 30, 2025 Read →](https://www.casi.org/articles/what-are-keystone-probiotic-species)

### [![Orexin, Circadian Timing, & Sleep Dynamics: Clinical Implications on HPA Activity](https://www.casi.org/hs-fs/hubfs/casi/featured/oct-21-orexin-circadian-timing.jpeg?width=960) Research & Education Orexin, Circadian Timing, & Sleep Dynamics: Clinical Implications on HPA Activity Orexin, a neuropeptide that governs wakefulness and circadian timing, links disrupted sleep to HPA axis overactivation and elevated cortisol. Oct 21, 2025 Read →](https://www.casi.org/articles/orexin-circadian-timing-sleep-dynamics-hpa-activity)

### [![Hanging Out with Prebiotic Nitrate: A New Frontier in Oral Health](https://www.casi.org/hs-fs/hubfs/casi/featured/oct-16-hanging-out-prebiotic-nitrate.jpeg?width=960) Science Update Hanging Out with Prebiotic Nitrate: A New Frontier in Oral Health Dietary nitrate delivered via chewing gum may shift the oral microbiome toward beneficial bacteria within hours, a small pilot study found. Oct 16, 2025 Read →](https://www.casi.org/articles/prebiotic-nitrate-new-frontier-oral-health)

### [![A New Way to Support Cartilage for Healthy Movement This Fall](https://www.casi.org/hs-fs/hubfs/casi/featured/sept-30-new-way-to-support-cartilage.jpeg?width=960) Research & Education A New Way to Support Cartilage for Healthy Movement This Fall Boswellia serrata and celery seed extract combined in a clinical trial reduced knee osteoarthritis pain, stiffness, and improved mobility. Oct 06, 2025 Read →](https://www.casi.org/articles/support-cartilage-healthy-movement)

### [![The Citrus Polyphenol Advantage: Red Orange Complex™ for Skin, Hair, and Nails](https://www.casi.org/hs-fs/hubfs/casi/featured/adobestock_76458684.jpeg?width=960) Research & Education The Citrus Polyphenol Advantage: Red Orange Complex™ for Skin, Hair, and Nails Red Orange Complex, a standardized blood orange extract, has been shown in clinical trials to support skin hydration, elasticity, and photoprotection. Sep 25, 2025 Read →](https://www.casi.org/articles/citrus-polyphenol-red-orange-complex)

### [![The 8 Most Clinically Relevant Mushrooms to Know About in 2025](https://www.casi.org/hs-fs/hubfs/casi/featured/sept-18-clinically-relevant-mushrooms.jpeg?width=960) Research & Education The 8 Most Clinically Relevant Mushrooms to Know About in 2025 Eight mushrooms, including reishi, lion's mane, and cordyceps, contain compounds like beta-glucans shown to support immune, brain, and metabolic health. Sep 18, 2025 Read →](https://www.casi.org/articles/8-clinically-relevant-mushrooms-2025)

### [![Parallels in Butyrate Delivery: Comparative Insights into Tri-Butyrin and Anaerostipes](https://www.casi.org/hs-fs/hubfs/casi/featured/sept-16-tri-butyrin-anaerostipes.jpeg?width=960) Research & Education Parallels in Butyrate Delivery: Comparative Insights into Tri-Butyrin and Anaerostipes Explore the roles of tri-butyrin and Anaerostipes in gut health, their synergistic effects on butyrate production… Sep 16, 2025 Read →](https://www.casi.org/articles/butyrate-delivery-tri-butyrin-anaerostipes)

### [![5 Benefits You Need to Know About Ergothioneine](https://www.casi.org/hs-fs/hubfs/casi/featured/sept-11-5-benefits-ergothioneine.jpeg?width=960) Research & Education 5 Benefits You Need to Know About Ergothioneine Ergothioneine, an amino acid found mainly in mushrooms, is studied for roles in brain health, antioxidant status, and healthy aging. Sep 11, 2025 Read →](https://www.casi.org/articles/5-benefits-ergothioneine)

### [![Combined Resistance Training and Vicia faba Supplementation Promotes Strength and Endurance in Both Men and Women: A Randomized Trial](https://www.casi.org/hs-fs/hubfs/casi/featured/sept-2-resistance-training-vicia-faba.jpeg?width=960) Science Update Combined Resistance Training and Vicia faba Supplementation Promotes Strength and Endurance in Both Men and Women: A Randomized Trial A randomized trial found that fava bean peptides plus resistance training improved leg strength, endurance, and bone mineral content in both sexes. Sep 04, 2025 Read →](https://www.casi.org/articles/resistance-training-vicia-faba-supplementation)

### [![Fueling the Gut: How Anaerostipes Caccae Powers Butyrate Production](https://www.casi.org/hs-fs/hubfs/casi/featured/aug-28-fueling-the-gut-anaerostipes.jpeg?width=960) Research & Education Fueling the Gut: How Anaerostipes Caccae Powers Butyrate Production Anaerostipes caccae, a gut bacterium, ferments carbohydrates and cross-feeds on other microbes' byproducts to produce butyrate for gut health. Aug 28, 2025 Read →](https://www.casi.org/articles/fueling-gut-anaerostipes-caccae-butyrate-production)

### [![GLP-1 Begins in the Gut: Clinical Clues From Microbiome Testing](https://www.casi.org/hs-fs/hubfs/casi/archive/aug-19-glp-gut.jpg?width=960) Research & Education GLP-1 Begins in the Gut: Clinical Clues From Microbiome Testing Gut bacteria shape GLP-1 secretion through short-chain fatty acids and bile acid signaling, and stool testing may reveal microbial clues to hormone output. Aug 19, 2025 Read →](https://www.casi.org/articles/glp-1-gut-microbiome-testing)

### [![A Case Report on Trans-Geranylgeraniol Supplementation in a 27-Year-Old Male with Thyroid Dysfunction](https://www.casi.org/hs-fs/hubfs/casi/featured/aug-14-trans-geranylgeraniol-testosterone.jpeg?width=960) Science Update A Case Report on Trans-Geranylgeraniol Supplementation in a 27-Year-Old Male with Thyroid Dysfunction Trans-geranylgeraniol supplementation in a man with Hashimoto's thyroiditis and low testosterone preceded a near doubling of his testosterone levels. Aug 14, 2025 Read →](https://www.casi.org/articles/case-report-trans-geranylgeraniol-supplementation-thyroid-dysfunction)

### [![A Case Report on a Personalized Six-Month Nutraceutical and Dietary Protocol Supporting a 60-Year-Old Male with Metabolic Dysfunction](https://www.casi.org/hs-fs/hubfs/casi/featured/aug-5-case-report-60-year-old-male.jpeg?width=960) Science Update A Case Report on a Personalized Six-Month Nutraceutical and Dietary Protocol Supporting a 60-Year-Old Male with Metabolic Dysfunction A six month Mediterranean diet and nutraceutical protocol supported drops in blood glucose, triglycerides and cholesterol in a man with metabolic syndrome. Aug 05, 2025 Read →](https://www.casi.org/articles/case-report-nutraceutical-dietary-protocol-metabolic-dysfunction)

### [![Two Next-Generation Probiotics You Should Know About: Anaerostipes and Akkermansia](https://www.casi.org/hs-fs/hubfs/casi/featured/july-31-two-next-gen-probiotics.jpeg?width=960) Research & Education Two Next-Generation Probiotics You Should Know About: Anaerostipes and Akkermansia Akkermansia muciniphila and Anaerostipes caccae, two next-generation probiotics, cross-feed to produce butyrate and support gut barrier health. Jul 31, 2025 Read →](https://www.casi.org/articles/next-generation-probiotics-anaerostipes-akkermansia)

### [![Foundations of GLP-1 Support: Nutritional and Lifestyle Strategies for Healthy Glucose Metabolism](https://www.casi.org/hs-fs/hubfs/casi/archive/july-17-foundations-of-glp-1-support_5.jpg?width=960) Research & Education Foundations of GLP-1 Support: Nutritional and Lifestyle Strategies for Healthy Glucose Metabolism GLP-1 supports glucose regulation, and fiber-rich diets, probiotics, magnesium, and botanicals like berberine may support its natural production. Jul 17, 2025 Read →](https://www.casi.org/articles/foundations-of-glp-1-support-nutritional-and-lifestyle-strategies-for-healthy-glucose-metabolism)

### [![GLP-1s and Hydration: What You Need to Know](https://www.casi.org/hs-fs/hubfs/casi/archive/july-11-glp-1-and-hydration.jpg?width=960) Research & Education GLP-1s and Hydration: What You Need to Know GLP-1 receptor agonists can affect hydration through appetite suppression, GI side effects, and higher carbohydrate intake, which raises water needs. Jul 11, 2025 Read →](https://www.casi.org/articles/glp-1s-and-hydration-what-you-need-to-know)

### [![The Microbiome-Allergy Connection: Probiotics in Clinical Practice](https://www.casi.org/hs-fs/hubfs/casi/featured/july-8-the_microbiome-allergy-connection.jpeg?width=960) Research & Education The Microbiome-Allergy Connection: Probiotics in Clinical Practice Probiotic strains such as Lactobacillus, Bifidobacterium, and Bacillus may support immune tolerance and ease seasonal or environmental allergy symptoms. Jul 08, 2025 Read →](https://www.casi.org/articles/microbiome-allergy-connection-probiotics-in-clinical-practice)

### [![An Update on the Science of Skin: PeptiYouth™](https://www.casi.org/hs-fs/hubfs/casi/featured/july-3-update-on-the-science-of-skin.jpeg?width=960) Science Update An Update on the Science of Skin: PeptiYouth™ PeptiYouth, an AI-discovered peptide, reduced wrinkle depth in a clinical trial and boosted collagen and elastin synthesis in skin cells. Jul 03, 2025 Read →](https://www.casi.org/articles/update-on-the-science-of-skin-peptiyouth)

### [![From Nature to Nutraceutical: Look Out for Adulteration in Herbal Supplements](https://www.casi.org/hs-fs/hubfs/casi/featured/june-24-from-nature-to-nutraceutical.jpeg?width=960) Research & Education From Nature to Nutraceutical: Look Out for Adulteration in Herbal Supplements Herbal supplements like black cohosh face frequent adulteration through species substitution and dilution, and cGMP testing helps verify quality. Jun 24, 2025 Read →](https://www.casi.org/articles/from-nature-to-nutraceutical-look-out-for-adulteration-in-herbal-supplements)

### [![The Hidden Connection Between Erectile Dysfunction and Antioxidant Status](https://www.casi.org/hs-fs/hubfs/casi/featured/65973ff2-5499-49ce-af3f-bbf57aabf3f9.jpg?width=960) Research & Education The Hidden Connection Between Erectile Dysfunction and Antioxidant Status Oxidative stress and endothelial dysfunction are closely tied to erectile dysfunction, and antioxidants like vitamin C and E may support vascular health. Jun 10, 2025 Read →](https://www.casi.org/articles/hidden-connection-between-erectile-dysfunction-and-antioxidant-status)

### [![The Drug-Nutrient Interactions that Impact the Two Most Commonly Prescribed Medications](https://www.casi.org/hs-fs/hubfs/casi/featured/june-5-the_drug-nutrient-interactions.jpeg?width=960) Research & Education The Drug-Nutrient Interactions that Impact the Two Most Commonly Prescribed Medications Statins and metformin, two of the most prescribed drugs in the US, can deplete CoQ10 and vitamin B12, raising myopathy and neuropathy risks. Jun 06, 2025 Read →](https://www.casi.org/articles/drug-nutrient-interactions-that-impact-two-most-commonly-prescribed-medications)

### [![Bridging Regeneration and Repair: The Critical Role of Stem and Progenitor Cells](https://www.casi.org/hs-fs/hubfs/casi/featured/may-27-bridging-regeneration-and-repair.jpeg?width=960) Research & Education Bridging Regeneration and Repair: The Critical Role of Stem and Progenitor Cells Stem and progenitor cells regenerate tissue, and endothelial progenitor cells specifically support vascular repair tied to cardiovascular disease risk. May 27, 2025 Read →](https://www.casi.org/articles/bridging-regeneration-repair-critical-role-stem-progenitor-cells)

### [![Peptides in Action: The Expanding Role of Bioactive Peptides in Human Health](https://www.casi.org/hs-fs/hubfs/casi/featured/may-22-peptides-in-action.jpeg?width=960) Research & Education Peptides in Action: The Expanding Role of Bioactive Peptides in Human Health Bioactive peptides like PeptiStrong and PeptiYouth show early trial results supporting muscle strength recovery after exercise and reduced wrinkle depth. May 22, 2025 Read →](https://www.casi.org/articles/peptides-in-action-expanding-role-bioactive-peptides-human-health)

### [![The Role of Phytonutrient-Rich Superfoods in Immune, Brain, and Heart Health](https://www.casi.org/hs-fs/hubfs/casi/featured/may-13-role-of-phytonutrients-new.jpeg?width=960) Research & Education The Role of Phytonutrient-Rich Superfoods in Immune, Brain, and Heart Health Phytonutrient-rich superfoods like berries, spirulina, and nettle are shown to support immune, heart, and cognitive health. May 14, 2025 Read →](https://www.casi.org/articles/role-phytonutrient-rich-superfoods-in-immune-brain-heart-health)

### [![Phyto-Fuel: The Role of Phytochemicals in Supporting Antioxidant Status and Metabolic Health](https://www.casi.org/hs-fs/hubfs/casi/featured/adobestock_412681837.jpeg?width=960) Research & Education Phyto-Fuel: The Role of Phytochemicals in Supporting Antioxidant Status and Metabolic Health Phytochemicals like flavonoids, carotenoids, and polyphenols support antioxidant status, healthy blood sugar, and lipid metabolism. May 08, 2025 Read →](https://www.casi.org/articles/phyto-fuel-role-of-phytochemicals-supporting-antioxidant-status-metabolic-health)

### [![A New Reason to Include More Color in Your Meals: Radiant, Healthy-Looking Skin](https://www.casi.org/hs-fs/hubfs/casi/featured/may-1-new-reason-to-include-color.jpeg?width=960) Research & Education A New Reason to Include More Color in Your Meals: Radiant, Healthy-Looking Skin Phytochemicals like carotenoids and cocoa flavanols in colorful produce may support skin's antioxidant status, hydration, and resistance to UV damage. May 02, 2025 Read →](https://www.casi.org/articles/new-reason-include-more-color-in-meals-radiant-healthy-looking-skin)

### [![Four Unique Probiotic Strains That Help Promote a Healthy Vaginal Microbiome](https://www.casi.org/hs-fs/hubfs/casi/featured/4-24-probiotic-strains-vaginal-health.jpeg?width=960) Research & Education Four Unique Probiotic Strains That Help Promote a Healthy Vaginal Microbiome L. crispatus, L. jensenii, L. gasseri and L. rhamnosus support vaginal health by producing lactic acid and limiting pathogen growth. Apr 24, 2025 Read →](https://www.casi.org/articles/four-unique-probiotic-strains-help-promote-healthy-vaginal-microbiome)

### [![What Are Oxalates, and Should You Avoid Them?](https://www.casi.org/hs-fs/hubfs/casi/featured/april-23-what-are-oxalates.jpeg?width=960) Research & Education What Are Oxalates, and Should You Avoid Them? Oxalates in plant foods can hinder nutrient absorption, and dietary strategies like reducing sodium and boosting calcium may lower kidney stone risk. Apr 23, 2025 Read →](https://www.casi.org/articles/what-are-oxalates-should-you-avoid-them)

### [![Can Short-Chain Fatty Acids Elevate Your Exercise Routine?](https://www.casi.org/hs-fs/hubfs/casi/featured/april-22-polyphenols.jpeg?width=960) Research & Education Can Short-Chain Fatty Acids Elevate Your Exercise Routine? Explore how short-chain fatty acids and polyphenols can enhance athletic performance, recovery, and gut health… Apr 22, 2025 Read →](https://www.casi.org/articles/can-short-chain-fatty-acids-elevate-your-exercise-routine)

### [![Wellness Essentials: The Role of Key Nutrients in Women's Health at Every Stage](https://www.casi.org/hs-fs/hubfs/casi/featured/april-15-the_role-of-key-nutrients-in-womens-health.jpeg?width=960) Research & Education Wellness Essentials: The Role of Key Nutrients in Women's Health at Every Stage Iron, calcium, magnesium, and folate needs shift across adolescence, pregnancy, and menstrual cycles, and many women fall short of recommended intakes. Apr 18, 2025 Read →](https://www.casi.org/articles/wellness-essentials-role-of-key-nutrients-in-womens-health)

### [![Eggplant – Antioxidants & Anthocyanins](https://www.casi.org/hs-fs/hubfs/casi/featured/583.jpg?width=960) Research & Education Eggplant – Antioxidants & Anthocyanins Eggplant skin contains anthocyanins like nasunin that scavenge free radicals and protect cells, while the fruit stays low in calories and high in fiber. Apr 15, 2025 Read →](https://www.casi.org/articles/eggplant-antioxidants-anthocyanins)

### [![Healthy Summer Skin: Lifestyle & Nutrient Factors for Sun-Exposed Days](https://www.casi.org/hs-fs/hubfs/casi/featured/april-10-healthy-summer-skin.jpeg?width=960) Research & Education Healthy Summer Skin: Lifestyle & Nutrient Factors for Sun-Exposed Days Omega-3s, vitamins C and E, and carotenoids may help protect skin from sun-related damage and support healthy skin aging, per recent research. Apr 10, 2025 Read →](https://www.casi.org/articles/healthy-summer-skin-lifestyle-nutrient-factors-for-sun-exposed-days)

### [![Exploring the Spectrum of 'Normal' B12 Levels: An Observational Study in Neurological Health](https://www.casi.org/hs-fs/hubfs/casi/featured/april-8-exploring-spectrum-b12.jpeg?width=960) Science Update Exploring the Spectrum of 'Normal' B12 Levels: An Observational Study in Neurological Health B12 levels at both the low and high end of the 'normal' range were linked to neurological changes in a 2025 study of 231 older adults. Apr 08, 2025 Read →](https://www.casi.org/articles/exploring-spectrum-of-normal-b12-levels-observational-study-in-neurological-health)

### [![Why Magnesium is Still the Crown Jewel for Supporting Sleep](https://www.casi.org/hs-fs/hubfs/casi/archive/april-1-magnesium-crown-jewel.jpg?width=960) Research & Education Why Magnesium is Still the Crown Jewel for Supporting Sleep Magnesium may support sleep quality and stress response, and one trial reported a 44.9 percent reduction in stress scores after eight weeks. Apr 01, 2025 Read →](https://www.casi.org/articles/why-magnesium-is-still-the-crown-jewel-for-supporting-sleep)

### [![Top Tips for Stimulating the Vagus Nerve and Supporting the Gut-Brain Axis](https://www.casi.org/hs-fs/hubfs/casi/archive/march-27-stimulating-vagus-nerve.jpg?width=960) Research & Education Top Tips for Stimulating the Vagus Nerve and Supporting the Gut-Brain Axis The vagus nerve links gut and brain function, and humming, cold exposure, deep breathing, and probiotic foods may help strengthen vagal tone. Mar 27, 2025 Read →](https://www.casi.org/articles/top-tips-for-stimulating-the-vagus-nerve-and-supporting-the-gut-brain-axis)

### [![Lift Your Mood: The Role of Physical Activity in Mental Health](https://www.casi.org/hs-fs/hubfs/casi/featured/march-18-lift-your-mood-physical-activity_0.jpeg?width=960) Research & Education Lift Your Mood: The Role of Physical Activity in Mental Health Aerobic and strength exercise supports mental health via neurotrophic factors and myokines, aided by nutrients like collagen and creatine. Mar 14, 2025 Read →](https://www.casi.org/articles/lift-your-mood-role-of-physical-activity-in-mental-health)

### [![Why Creatine Supplementation Should Be a Top Consideration for Women: Supporting Physical Health and Beyond](https://www.casi.org/hs-fs/hubfs/casi/featured/march-13-creatine-supplementation.jpeg?width=960) Research & Education Why Creatine Supplementation Should Be a Top Consideration for Women: Supporting Physical Health and Beyond Creatine supplementation may support women's muscle strength, bone density, body composition, and cognitive function as hormonal changes accompany aging. Mar 14, 2025 Read →](https://www.casi.org/articles/creatine-supplementation-should-be-top-consideration-for-women-supporting-physical-health)

### [![Nutrient Gaps: 5 Things to Do and Avoid in 2025](https://www.casi.org/hs-fs/hubfs/casi/featured/march-4-nutrient-gaps.jpeg?width=960) Research & Education Nutrient Gaps: 5 Things to Do and Avoid in 2025 Most Americans fall short on vegetables, dairy, and nutrients like vitamin D, while ultra-processed foods and GLP-1 medications worsen the gaps. Mar 04, 2025 Read →](https://www.casi.org/articles/nutrient-gaps-5-things-to-do-and-avoid-in-2025)

### [![Clinical Trial Compares Vicia faba Peptides to Milk Protein in Promoting Muscle Protein Synthesis During Remobilization](https://www.casi.org/hs-fs/hubfs/casi/featured/feb-27-clinical-trial-compares-vicia-faba-peptides-to-milk-protein.jpeg?width=960) Science Update Clinical Trial Compares Vicia faba Peptides to Milk Protein in Promoting Muscle Protein Synthesis During Remobilization Fava bean peptides matched milk protein in limiting muscle loss during immobilization and showed greater protein synthesis during recovery. Feb 27, 2025 Read →](https://www.casi.org/articles/vicia-faba-peptides-milk-protein-promoting-muscle-protein-synthesis-remobilization)

### [![Randomized Controlled Trial Investigates PeptiStrong™ Supplementation on Muscle Strength Recovery & Restoration After Resistance Exercise](https://www.casi.org/hs-fs/hubfs/casi/featured/feb-18-randomized-controlled-trial-investigates-peptistrong.jpeg?width=960) Science Update Randomized Controlled Trial Investigates PeptiStrong™ Supplementation on Muscle Strength Recovery & Restoration After Resistance Exercise A randomized trial found PeptiStrong, a plant-based peptide, preserved muscle strength and reduced fatigue after resistance exercise compared to placebo. Feb 18, 2025 Read →](https://www.casi.org/articles/trial-investigates-peptistrong-supplementation-muscle-strength-recovery-restoration)

### [![Serum Bovine Immunoglobulin: A Dairy-Free Alternative to Colostrum for Gut Integrity and Immune Support](https://www.casi.org/hs-fs/hubfs/casi/featured/jan-15-serum-bovine-immunoglobulin_1.jpeg?width=960) Research & Education Serum Bovine Immunoglobulin: A Dairy-Free Alternative to Colostrum for Gut Integrity and Immune Support Serum-derived bovine immunoglobulin offers a dairy-free alternative to colostrum for binding gut antigens and supporting intestinal barrier integrity. Feb 11, 2025 Read →](https://www.casi.org/articles/serum-bovine-immunoglobulin-dairy-free-alternative-colostrum)

### [![Who Benefits from N-Acetyl-D-Glucosamine (NAG)? Exploring Its Role in Supporting Gut Health and Barrier Integrity](https://www.casi.org/hs-fs/hubfs/casi/featured/feb-6-who_benefits_from_n-acetyl-d-glucosamine.jpeg?width=960) Research & Education Who Benefits from N-Acetyl-D-Glucosamine (NAG)? Exploring Its Role in Supporting Gut Health and Barrier Integrity N-acetyl-D-glucosamine supports gut mucin formation and limits E. coli biofilm, and eased IBD symptoms in a clinical trial. Feb 06, 2025 Read →](https://www.casi.org/articles/benefits-n-acetyl-d-glucosamine-supporting-gut-health-barrier-integrity)

### [![Serum Bovine Immunoglobulin: Promoting Short-Chain Fatty Acid (SFCA) Production and Gut Microbiota Balance](https://www.casi.org/hs-fs/hubfs/casi/featured/jan-15-serum-bovine-immunoglobulin.jpeg?width=960) Research & Education Serum Bovine Immunoglobulin: Promoting Short-Chain Fatty Acid (SFCA) Production and Gut Microbiota Balance Serum bovine immunoglobulins support gut microbiota balance by binding harmful compounds and promoting short-chain fatty acid production in the colon. Jan 28, 2025 Read →](https://www.casi.org/articles/serum-bovine-immunoglobulin-promoting-short-chain-fatty-acid-production-gut-microbiota-balance)

### [![Serum Bovine Immunoglobulin in Action: Supporting the Remove and Revive Phases in the 5R Program](https://www.casi.org/hs-fs/hubfs/casi/featured/jan-30-serum_bovine_immunoglobulin_in_action.jpeg?width=960) Research & Education Serum Bovine Immunoglobulin in Action: Supporting the Remove and Revive Phases in the 5R Program Serum-derived bovine immunoglobulin may support the Remove and Revive phases of the 5R gut protocol, reducing endotoxemia and easing IBS symptoms. Jan 16, 2025 Read →](https://www.casi.org/articles/serum-bovine-immunoglobulin-supporting-remove-and-revive-phases-5r-program)

### [![N-Acetyl-D-Glucosamine: A Key Player in Balanced Immune and Healthy Inflammatory Responses](https://www.casi.org/hs-fs/hubfs/casi/featured/feb-13-n-acetyl-d-glucosamine-key-player-in-balanced-immune.jpeg?width=960) Research & Education N-Acetyl-D-Glucosamine: A Key Player in Balanced Immune and Healthy Inflammatory Responses NAG, an amino sugar derived from glucosamine, supports balanced immune and inflammatory responses, and clinical trials link it to eased IBD symptoms. Jan 15, 2025 Read →](https://www.casi.org/articles/n-acetyl-d-glucosamine-balanced-immune-and-healthy-inflammatory-responses)

### [![Digestive Enzymes: A Key to Gut Health](https://www.casi.org/hs-fs/hubfs/casi/featured/jan-9-digestive-enzymes.jpeg?width=960) Research & Education Digestive Enzymes: A Key to Gut Health Amylase, protease, and lipase enable digestion of macronutrients, and research shows enteric coating helps these enzymes remain effective. Jan 09, 2025 Read →](https://www.casi.org/articles/digestive-enzymes-a-key-to-gut-health)

### [![The 5R Blueprint for Gut Health](https://www.casi.org/hs-fs/hubfs/casi/featured/jan-7-5r-blueprint-for-gut-health.jpeg?width=960) Research & Education The 5R Blueprint for Gut Health Five phases, Remove, Replace, Replenish, Revive, and Rebalance, structure this blueprint for restoring gut microbial balance and mucosal health. Jan 07, 2025 Read →](https://www.casi.org/articles/the-5r-blueprint-for-gut-health)

### [![Revitalize and Rejuvenate: Harnessing Collagen Peptides for Recovery After Aesthetic Treatments](https://www.casi.org/hs-fs/hubfs/casi/featured/harnessing-collagen-peptides.jpeg?width=960) Research & Education Revitalize and Rejuvenate: Harnessing Collagen Peptides for Recovery After Aesthetic Treatments Oral collagen peptides may support skin hydration, elasticity, and healing, offering internal support alongside aesthetic treatments like microneedling. Dec 17, 2024 Read →](https://www.casi.org/articles/harnessing-collagen-peptides-for-recovery-after-aesthetic-treatments)

### [![Peppermint: The Star of the Holiday Season](https://www.casi.org/hs-fs/hubfs/casi/featured/12-3-peppermint-star-of-holidays.jpeg?width=960) Research & Education Peppermint: The Star of the Holiday Season Peppermint's menthol activates cold-sensing TRPM8 receptors, and the herb has been studied for supporting digestion, mood, sore muscles, and detox. Dec 04, 2024 Read →](https://www.casi.org/articles/peppermint-the-star-of-the-holiday-season)

### [![Getting to the Root – How Two Novel Nutraceuticals Work Together to Promote Clear Skin](https://www.casi.org/hs-fs/hubfs/casi/featured/11-26-sebum-production.jpeg?width=960) Research & Education Getting to the Root – How Two Novel Nutraceuticals Work Together to Promote Clear Skin Pantothenic acid and carnitine work together to normalize sebum production and support keratinocytes, showing reduced acne lesions in trials. Nov 27, 2024 Read →](https://www.casi.org/articles/how-two-novel-nutraceuticals-work-together-promote-clear-skin)

### [![Thankful for Tryptophan](https://www.casi.org/hs-fs/hubfs/casi/featured/11-19-thankful-for-tryptophan.jpeg?width=960) Research & Education Thankful for Tryptophan Turkey is rich in tryptophan, an amino acid that supports serotonin and melatonin, and studies link higher intake to better mood, sleep, and heart health. Nov 19, 2024 Read →](https://www.casi.org/articles/thankful-for-tryptophan)

### [![3 Surprising Compounds Needed for Optimal Insulin Metabolism](https://www.casi.org/hs-fs/hubfs/casi/featured/11-14-compounds-for-insulin.jpeg?width=960) Research & Education 3 Surprising Compounds Needed for Optimal Insulin Metabolism Lipoic acid, carnosine, and taurine show antioxidant and glucose-lowering effects in clinical studies of insulin resistance and type 2 diabetes. Nov 15, 2024 Read →](https://www.casi.org/articles/3-surprising-compounds-needed-for-optimal-insulin-metabolism)

### [![Clear Evidence: The Role of Spore-Based Probiotics in Healthy-Looking Skin](https://www.casi.org/hs-fs/hubfs/casi/featured/11-12-role-of-spore-based-healthy-skin.jpeg?width=960) Research & Education Clear Evidence: The Role of Spore-Based Probiotics in Healthy-Looking Skin Spore-based probiotics support a balanced gut microbiome, and studies link them to improved skin barrier function and reduced acne. Nov 11, 2024 Read →](https://www.casi.org/articles/clear-evidence-role-of-spore-based-probiotics-in-healthy-looking-skin)

### [![Berberine – The Missing Link in Blood Glucose Management?](https://www.casi.org/hs-fs/hubfs/casi/featured/11-5-berberine-missing-link-diabetes.jpeg?width=960) Research & Education Berberine – The Missing Link in Blood Glucose Management? Berberine, a plant alkaloid, is linked to lower HbA1c, fasting glucose, insulin resistance, lipids, and CRP in adults with type 2 diabetes. Nov 05, 2024 Read →](https://www.casi.org/articles/berberine-missing-link-in-blood-glucose-management)

### [![Hormones: The Alchemists of Skin and Hair Health](https://www.casi.org/hs-fs/hubfs/casi/featured/10-31-hormones-hair-skin.jpeg?width=960) Research & Education Hormones: The Alchemists of Skin and Hair Health Estrogen and progesterone shape skin elasticity, hydration, and hair growth cycles, and nutrients like DIM and chaste tree may support that balance. Oct 31, 2024 Read →](https://www.casi.org/articles/hormones-alchemists-of-skin-and-hair-health)

### [![Magnesium L-Threonate: Champion of Cognitive Health](https://www.casi.org/hs-fs/hubfs/casi/featured/10-22-magnesium-l-threonate_0.jpeg?width=960) Research & Education Magnesium L-Threonate: Champion of Cognitive Health L-threonate-bound magnesium crosses the blood-brain barrier and has been shown in trials to support memory, cognition, and executive function. Oct 22, 2024 Read →](https://www.casi.org/articles/magnesium-l-threonate-champion-of-cognitive-health)

### [![Muscle Tone & Metabolism: Sculpting from the Inside Out](https://www.casi.org/hs-fs/hubfs/casi/featured/10-17-muscle-tone-and-metabolism.jpeg?width=960) Research & Education Muscle Tone & Metabolism: Sculpting from the Inside Out Muscle tone acts through myokines to support insulin sensitivity, with collagen, creatine, and leucine shown to help maintain it. Oct 15, 2024 Read →](https://www.casi.org/articles/muscle-tone-and-metabolism-sculpting-from-the-inside-out)

### [![Why Does Nutrition Belong at the Center of Every Aesthetic Practice?](https://www.casi.org/hs-fs/hubfs/casi/featured/10-10-why-does-nutrition-belong.jpeg?width=960) Research & Education Why Does Nutrition Belong at the Center of Every Aesthetic Practice? Nutrition shapes skin health through barrier support, hormonal balance, the gut-skin axis, and collagen synthesis, vitamin C among the key nutrients. Oct 10, 2024 Read →](https://www.casi.org/articles/why-does-nutrition-belong-at-center-of-every-aesthetic-practice)

### [![Decoding Peptides: The Body’s Little Helpers](https://www.casi.org/hs-fs/hubfs/casi/featured/10-1-decoding-peptides.jpeg?width=960) Research & Education Decoding Peptides: The Body’s Little Helpers Fava bean derived bioactive peptides such as PeptiStrong have been shown in trials to speed muscle strength recovery after exhaustive exercise in adults. Sep 30, 2024 Read →](https://www.casi.org/articles/decoding-peptides-bodys-little-helpers)

### [![Bioactive Peptides From the Fava Bean: The Future of Muscular Health?](https://www.casi.org/hs-fs/hubfs/casi/featured/9-26-bioactive-peptides.jpeg?width=960) Research & Education Bioactive Peptides From the Fava Bean: The Future of Muscular Health? Fava bean derived peptides supported muscle strength recovery, reduced fatigue, and matched milk protein for muscle regain after immobilization. Sep 25, 2024 Read →](https://www.casi.org/articles/bioactive-peptides-from-the-fava-bean-future-of-muscular-health)

### [![Skin Health is Gene Deep](https://www.casi.org/hs-fs/hubfs/casi/featured/skin-health-gene-deep-9-17.jpeg?width=960) Research & Education Skin Health is Gene Deep Genetic variations in GLO1, FUT2, SOD2, and FLG influence skin aging, gut bacteria balance, antioxidant status, and skin barrier function. Sep 18, 2024 Read →](https://www.casi.org/articles/skin-health-is-gene-deep)

### [![Omega-3 Fatty Acids: Balancing Your Skin From the Inside Out](https://www.casi.org/hs-fs/hubfs/casi/featured/9-12-omega-3-fatty.jpeg?width=960) Research & Education Omega-3 Fatty Acids: Balancing Your Skin From the Inside Out Omega-3 fatty acids support skin barrier function, hydration, and a healthy inflammatory response, with evidence for benefits in acne and photoaging. Sep 13, 2024 Read →](https://www.casi.org/articles/omega-3-fatty-acids-balancing-skin-inside-out)

### [![4 Surprising Botanicals to Promote Normal GLP-1 Production](https://www.casi.org/hs-fs/hubfs/casi/featured/9-3-suprising-botanicals.jpeg?width=960) Research & Education 4 Surprising Botanicals to Promote Normal GLP-1 Production Berberine, fenugreek, American ginseng, and gymnema may support GLP-1 production and healthy blood sugar and insulin metabolism, research suggests. Sep 03, 2024 Read →](https://www.casi.org/articles/4-surprising-botanicals-promote-normal-glp-1-production)

### [![Vitamins E & C: The Antioxidant Power Couple for Radiant Skin](https://www.casi.org/hs-fs/hubfs/casi/featured/8-29-vitaminc-e-antioxidant.jpeg?width=960) Research & Education Vitamins E & C: The Antioxidant Power Couple for Radiant Skin Antioxidant vitamins E and C support skin health, with tocotrienols affecting melanin and topical use improving tone and elasticity in a trial. Aug 29, 2024 Read →](https://www.casi.org/articles/vitamins-e-and-c-antioxidant-power-radiant-skin)

### [![Hungry for More: Nutrition Gaps in the Modern American Diet](https://www.casi.org/hs-fs/hubfs/casi/featured/8-20-hungry-for-more-american-diet.jpeg?width=960) Research & Education Hungry for More: Nutrition Gaps in the Modern American Diet Vitamin D, calcium, potassium, fiber, and iron intake fall short across most Americans, and soil depletion and GLP-1 agonist use compound the gap. Aug 20, 2024 Read →](https://www.casi.org/articles/nutrition-gaps-in-the-modern-american-diet)

### [![Nourish Your Beauty: Nutrients for a Radiant Skin Barrier](https://www.casi.org/hs-fs/hubfs/casi/featured/8-15-nourish-your-beauty.jpeg?width=960) Research & Education Nourish Your Beauty: Nutrients for a Radiant Skin Barrier Nutrients like protein, zinc, vitamins A, C, and E, and topical compounds such as CoQ10 support skin structure and counter aging-related damage. Aug 16, 2024 Read →](https://www.casi.org/articles/nourish-your-beauty-nutrients-for-radiant-skin-barrier)

### [![Spore-Based Probiotics: Guardians of Gut Health](https://www.casi.org/hs-fs/hubfs/casi/featured/8-6-spore-based-probiotics.jpeg?width=960) Research & Education Spore-Based Probiotics: Guardians of Gut Health Spore-based Bacillus probiotics survive stomach acid to germinate in the gut, where studies link them to microbiome balance and fewer GI symptoms. Aug 07, 2024 Read →](https://www.casi.org/articles/spore-based-probiotics-guardians-gut-health)

### [![Glowing Benefits: How Insulin and Glucose Metabolism Shape Your Skin](https://www.casi.org/hs-fs/hubfs/casi/featured/8-1-glowing-benefits-glucose.jpeg?width=960) Research & Education Glowing Benefits: How Insulin and Glucose Metabolism Shape Your Skin Discover how managing blood sugar and insulin metabolism can enhance skin health… Aug 01, 2024 Read →](https://www.casi.org/articles/how-insulin-and-glucose-metabolism-shape-skin)

### [![The Hidden Effects: Medications and Their Impact on Your GI Tract](https://www.casi.org/hs-fs/hubfs/casi/featured/7-23-hidden-effects-medications.jpeg?width=960) Research & Education The Hidden Effects: Medications and Their Impact on Your GI Tract Antibiotics, PPIs, NSAIDs, and GLP-1 agonists can disrupt gut function and the microbiome, and certain nutrients may help support the GI lining. Jul 23, 2024 Read →](https://www.casi.org/articles/medications-and-their-impact-on-gi-tract)

### [![Summer Glow: Tips to Tone Your Face and Support Skin Health](https://www.casi.org/hs-fs/hubfs/casi/featured/7-10-summer-glow-tips.jpeg?width=960) Research & Education Summer Glow: Tips to Tone Your Face and Support Skin Health Advanced glycation end products from cooking and sugar intake stiffen skin collagen, and gentler cooking methods may help reduce their impact. Jul 18, 2024 Read →](https://www.casi.org/articles/summer-glow-tips-to-tone-face-support-skin-health)

### [![Muscle Tone Matters: The Key to Optimal Body Composition and Metabolic Health](https://www.casi.org/hs-fs/hubfs/casi/featured/7-9-muscle-tone-matters.jpeg?width=960) Research & Education Muscle Tone Matters: The Key to Optimal Body Composition and Metabolic Health Muscle tone built through resistance training and nutrients like collagen, creatine, and leucine supports lean body mass and metabolic health. Jul 09, 2024 Read →](https://www.casi.org/articles/muscle-tone-matters-key-optimal-body-composition-metabolic-health)

### [![Simple Ways to Beat Summer Sneezes](https://www.casi.org/hs-fs/hubfs/casi/featured/7-3-beat-summer-sneezes.jpeg?width=960) Research & Education Simple Ways to Beat Summer Sneezes Bromelain, luteolin, and vitamin C may support mast cell stabilization and histamine metabolism to help ease seasonal allergy symptoms like sneezing. Jul 02, 2024 Read →](https://www.casi.org/articles/simple-ways-to-beat-summer-sneezes)

### [![Ten Nutrients to Help Your Skin Glow from the Inside Out](https://www.casi.org/hs-fs/hubfs/casi/featured/6-25-ten-nutrients-skin.jpeg?width=960) Research & Education Ten Nutrients to Help Your Skin Glow from the Inside Out Nutrients such as collagen peptides, vitamin C, and omega-3 fatty acids support skin hydration, elasticity, and structure from the inside out. Jun 25, 2024 Read →](https://www.casi.org/articles/ten-nutrients-help-skin-glow-from-the-inside-out)

### [![Taurine and Glycine: The Benefits of Combining These Two Amino Acids](https://www.casi.org/hs-fs/hubfs/casi/featured/6-20-taurine-glycine.jpeg?width=960) Research & Education Taurine and Glycine: The Benefits of Combining These Two Amino Acids Two conditionally essential amino acids, taurine and glycine, support metabolic, cardiovascular, and cognitive health as part of healthy aging. Jun 21, 2024 Read →](https://www.casi.org/articles/taurine-and-glycine-benefits-combining-amino-acids)

### [![The Versatility of Creatine: Going Beyond Sports Nutrition](https://www.casi.org/hs-fs/hubfs/casi/featured/6-3-versatility-of-creatine.jpeg?width=960) Research & Education The Versatility of Creatine: Going Beyond Sports Nutrition Creatine supports bone and muscle strength in postmenopausal women, muscle mass in aging adults, and offsets low creatine stores in vegetarians. Jun 12, 2024 Read →](https://www.casi.org/articles/versatility-of-creatine-beyond-sports-nutrition)

### [![Don’t Sleep on These Tips: Re-Set Your Sleep Routine](https://www.casi.org/hs-fs/hubfs/casi/featured/6-6-dont-sleep-on-these-tips.jpeg?width=960) Research & Education Don’t Sleep on These Tips: Re-Set Your Sleep Routine Magnesium, L-theanine, and GABA supplements, paired with consistent light and meal timing, may support healthier sleep and circadian rhythm regulation. Jun 06, 2024 Read →](https://www.casi.org/articles/sleep-tips-re-set-your-sleep-routine)

### [![Short-Chain Fatty Acids: What Are They and How Do They Support the Gut-Brain Axis?](https://www.casi.org/hs-fs/hubfs/casi/featured/5-28-short-chain-fatty-acids_0.jpeg?width=960) Research & Education Short-Chain Fatty Acids: What Are They and How Do They Support the Gut-Brain Axis? Short-chain fatty acids from fiber fermentation may support gut barrier integrity and reduce neuroinflammation along the gut-brain axis. May 28, 2024 Read →](https://www.casi.org/articles/short-chain-fatty-acids-how-support-gut-brain-axis)

### [![Omega-3s and Curcumin Supporting Inflammatory Pathways for Mental Health](https://www.casi.org/hs-fs/hubfs/casi/featured/5-23-omega3s-curcumin.jpeg?width=960) Research & Education Omega-3s and Curcumin Supporting Inflammatory Pathways for Mental Health Omega-3 fatty acids and curcumin may reduce inflammatory markers linked to depression, with evidence supporting their use alongside standard treatment. May 24, 2024 Read →](https://www.casi.org/articles/omega-3s-curcumin-supporting-inflammatory-pathways-mental-health)

### [![Probiotic Strains Associated with Positive Mental Health](https://www.casi.org/hs-fs/hubfs/casi/featured/5-14-probiotic-improved-mental-health_0.jpeg?width=960) Research & Education Probiotic Strains Associated with Positive Mental Health Specific Lactobacillus and Bifidobacterium strains support mood and cognition, with trials linking them to reduced anxiety, depression, and stress markers. May 14, 2024 Read →](https://www.casi.org/articles/probiotic-strains-associated-with-positive-mental-health)

### [![Magnesium Deficiency: How It Relates to Poor Mood and Mental Health](https://www.casi.org/hs-fs/hubfs/casi/featured/5-9-magnesium-deficiency-mood-mental-health.jpeg?width=960) Research & Education Magnesium Deficiency: How It Relates to Poor Mood and Mental Health Magnesium deficiency is linked to a higher risk of depression, and common causes include low dietary intake and long-term use of acid-reducing medications. May 06, 2024 Read →](https://www.casi.org/articles/magnesium-deficiency-how-relates-to-mood-and-mental-health)

### [![Ginkgo Biloba: Can it Promote Eye Health?](https://www.casi.org/hs-fs/hubfs/casi/featured/4-30-ginko-biloba-eye-health.jpeg?width=960) Research & Education Ginkgo Biloba: Can it Promote Eye Health? Antioxidant and circulatory effects of ginkgo may support eye health, improving ocular blood flow and visual field indices in glaucoma patients. Apr 30, 2024 Read →](https://www.casi.org/articles/ginkgo-biloba-promote-eye-health)

### [![Lactobacillus paracasei: Powerful Probiotic for Oral Microbial Balance](https://www.casi.org/hs-fs/hubfs/casi/featured/4-25-lactobacillus-paracasei-powerful-probiotic.jpeg?width=960) Research & Education Lactobacillus paracasei: Powerful Probiotic for Oral Microbial Balance Lactobacillus paracasei, a probiotic strain, lowered cariogenic bacteria levels and reduced dental caries risk in children in clinical trials. Apr 26, 2024 Read →](https://www.casi.org/articles/lactobacillus-paracasei-powerful-probiotic-oral-microbial-balance)

### [![Lutein and Zeaxanthin: Powerful Nutrients for Eye Health](https://www.casi.org/hs-fs/hubfs/casi/archive/sciupdate_12.jpg?width=960) Research & Education Lutein and Zeaxanthin: Powerful Nutrients for Eye Health Lutein and zeaxanthin accumulate in the retina, filtering blue light, and higher intake is linked to lower risk of advanced macular degeneration. Apr 11, 2024 Read →](https://www.casi.org/articles/lutein-zeaxanthin-powerful-nutrients-eye-health)

### [![The Truth About Mouthwash and Heart Health](https://www.casi.org/hs-fs/hubfs/casi/featured/4-9-mouthwash-cardiovascular.jpeg?width=960) Research & Education The Truth About Mouthwash and Heart Health Antibacterial mouthwash may harm oral bacteria needed for nitric oxide production, and frequent use is linked to higher blood pressure and diabetes risk. Apr 09, 2024 Read →](https://www.casi.org/articles/truth-about-mouthwash-and-heart-health)

### [![The Growing Connection Between Oral Microbiome and Cardiovascular Health](https://www.casi.org/hs-fs/hubfs/casi/featured/4-4-oral-microbiome-cardiovascular-health.jpeg?width=960) Research & Education The Growing Connection Between Oral Microbiome and Cardiovascular Health Periodontal disease and poor oral hygiene are linked to cardiovascular risk through inflammation, oral bacteria, and impaired nitric oxide production. Apr 04, 2024 Read →](https://www.casi.org/articles/growing-connection-oral-microbiome-cardiovascular-health)

### [![The Connection Between Autoimmune Diseases and Intestinal Permeability](https://www.casi.org/hs-fs/hubfs/casi/featured/3-28-autoimmune-gut-permeability.jpeg?width=960) Research & Education The Connection Between Autoimmune Diseases and Intestinal Permeability Intestinal permeability, or leaky gut, may let bacterial antigens trigger autoreactive immune cells linked to autoimmune disease. Mar 29, 2024 Read →](https://www.casi.org/articles/connection-between-autoimmune-diseases-intestinal-permeability)

### [![Vitamin D and Autoimmune Thyroiditis: Settling the Controversy](https://www.casi.org/hs-fs/hubfs/casi/featured/3-26-vitd-autoimmune-thyroiditis.jpeg?width=960) Research & Education Vitamin D and Autoimmune Thyroiditis: Settling the Controversy Vitamin D modulates immune function, and trials link it, alone or with selenium, to lower autoimmune disease risk and better thyroid markers. Mar 26, 2024 Read →](https://www.casi.org/articles/vitamin-d-and-autoimmune-thyroiditis)

### [![Vitamin K2 – The Missing Link in Osteoporosis?](https://www.casi.org/hs-fs/hubfs/casi/featured/microsoftteams-image_0.jpeg?width=960) Research & Education Vitamin K2 – The Missing Link in Osteoporosis? Vitamin K2 supports bone formation and strength, and clinical trials link its supplementation to increased bone density and fewer hip fractures. Mar 21, 2024 Read →](https://www.casi.org/articles/vitamin-k2-missing-link-osteoporosis)

### [![The Latest on Allergic Response and Gut Microbial Composition](https://www.casi.org/hs-fs/hubfs/casi/featured/3-19-allergic-response-gut-microbial.jpeg?width=960) Research & Education The Latest on Allergic Response and Gut Microbial Composition Gut microbial composition is tied to allergic conditions like rhinitis and eczema, and certain Bifidobacterium and Lactobacillus strains may ease symptoms. Mar 19, 2024 Read →](https://www.casi.org/articles/latest-on-allergic-response-gut-microbial-composition)

### [![The Thyroid-Gut Axis: Is There a Connection Between Thyroid Health and the Gut Microbiome?](https://www.casi.org/hs-fs/hubfs/casi/featured/3-12-thyroid-gut-axis.jpeg?width=960) Research & Education The Thyroid-Gut Axis: Is There a Connection Between Thyroid Health and the Gut Microbiome? Bidirectional communication between thyroid function and gut microbiota is linked to dysbiosis observed in patients with Graves disease. Mar 14, 2024 Read →](https://www.casi.org/articles/thyroid-gut-axis-connection-between-thyroid-health-gut-microbiome)

### [![Stinging Nettle: A Potent Herb to Support Immune Health](https://www.casi.org/hs-fs/hubfs/casi/featured/3-14-stinging-nettle-immune.jpeg?width=960) Research & Education Stinging Nettle: A Potent Herb to Support Immune Health Stinging nettle's vitamin C, iron and bioactive compounds may support immune health, and a trial found nettle extract eased allergic rhinitis symptoms. Mar 14, 2024 Read →](https://www.casi.org/articles/stinging-nettle-support-immune-health)

### [![Minerals to Promote Thyroid Health and Immune Function](https://www.casi.org/hs-fs/hubfs/casi/featured/3-5-minerals-thyroid-health.jpeg?width=960) Research & Education Minerals to Promote Thyroid Health and Immune Function Selenium, zinc, and magnesium support thyroid hormone regulation, and selenium supplementation has been shown to lower thyroid antibody levels. Mar 08, 2024 Read →](https://www.casi.org/articles/minerals-to-promote-thyroid-health-and-immune-function)

### [![Fight Common Environmental Triggers with Quercetin](https://www.casi.org/hs-fs/hubfs/casi/featured/3-7-quercetin-environmental.jpeg?width=960) Research & Education Fight Common Environmental Triggers with Quercetin Quercetin's effect on histamine and mast cell release may ease seasonal allergy symptoms, and a study found 200 mg daily improved quality-of-life scores. Mar 07, 2024 Read →](https://www.casi.org/articles/fight-common-environmental-triggers-with-quercetin)

### [![Gut Microbiome and Cardiovascular Health: What We Know About the Gut-Heart Axis](https://www.casi.org/hs-fs/hubfs/casi/featured/2-27-microbiome-cardiovascular.jpeg?width=960) Research & Education Gut Microbiome and Cardiovascular Health: What We Know About the Gut-Heart Axis The gut microbiome and its metabolites, especially short-chain fatty acids, appear linked to blood pressure regulation and cardiovascular disease risk. Feb 28, 2024 Read →](https://www.casi.org/articles/gut-microbiome-cardiovascular-health-gut-heart-axis)

### [![Vitamin C: Fueling Nitric Oxide for Healthy Blood Vessels](https://www.casi.org/hs-fs/hubfs/casi/featured/2-22-vitc-fueling-nitric-oxide.jpeg?width=960) Research & Education Vitamin C: Fueling Nitric Oxide for Healthy Blood Vessels Vitamin C supports nitric oxide production and endothelial health, helping sustain blood vessel function and normal blood pressure. Feb 22, 2024 Read →](https://www.casi.org/articles/vitamin-c-fueling-nitric-oxide-for-healthy-blood-vessels)

### [![Lifestyle Choices for Cardiovascular Wellness: The Latest Clinical Research](https://www.casi.org/hs-fs/hubfs/casi/featured/2-20-lifestyle-choices-cardiovascular-health.jpeg?width=960) Research & Education Lifestyle Choices for Cardiovascular Wellness: The Latest Clinical Research Blood sugar imbalance, smoking, vaping, toxin exposure, and chronic stress all shape cardiovascular risk, with certain nutrients offering support. Feb 20, 2024 Read →](https://www.casi.org/articles/lifestyle-choices-cardiovascular-wellness-latest-clinical-research)

### [![Nitric Oxide: The Key to Healthy Blood Pressure](https://www.casi.org/hs-fs/hubfs/casi/featured/2-15-nitric-oxide-healthy-blood-pressure.jpeg?width=960) Research & Education Nitric Oxide: The Key to Healthy Blood Pressure Nitric oxide acts as a vasodilator supporting healthy blood pressure, produced through an arginine pathway and a nitrate-dependent enterosalivary pathway. Feb 15, 2024 Read →](https://www.casi.org/articles/nitric-oxide-key-to-healthy-blood-pressure)

### [![Micronutrients to Promote Endothelial Integrity and Healthy Inflammatory Status](https://www.casi.org/hs-fs/hubfs/casi/featured/adobestock_691482157.jpeg?width=960) Research & Education Micronutrients to Promote Endothelial Integrity and Healthy Inflammatory Status Vitamin D, magnesium, rhamnan sulfate, and alpha-lipoic acid may help curb NF-kB activity, supporting endothelial health and inflammatory balance. Feb 13, 2024 Read →](https://www.casi.org/articles/micronutrients-endothelial-integrity-healthy-inflammatory-status)

### [![The Role of the Oral Microbiome on Nitric Oxide Production and Healthy Blood Pressure](https://www.casi.org/hs-fs/hubfs/casi/featured/2-8-oral-microbiome-nitric-oxide.jpeg?width=960) Research & Education The Role of the Oral Microbiome on Nitric Oxide Production and Healthy Blood Pressure Oral bacteria convert dietary nitrate into nitrite for nitric oxide production, and antibacterial mouthwash use has been linked to higher blood pressure. Feb 08, 2024 Read →](https://www.casi.org/articles/oral-microbiome-nitric-oxide-production-healthy-blood-pressure)

### [![The Latest Research on Antioxidative Status for Optimal Cardiovascular Health](https://www.casi.org/hs-fs/hubfs/casi/featured/2-6-antioxidative-status-cardiovascular.jpeg?width=960) Research & Education The Latest Research on Antioxidative Status for Optimal Cardiovascular Health Glutathione, Nrf2 activity, and selenium help govern antioxidative status, with a trial linking selenium and coQ10 to lower cardiovascular mortality risk. Feb 08, 2024 Read →](https://www.casi.org/articles/research-antioxidative-status-optimal-cardiovascular-health)

### [![The Intelligent Inner Lining of Blood Vessels: Nutrients that Support Vascular Health](https://www.casi.org/hs-fs/hubfs/casi/featured/1-30-intelligent-inner-lining.jpeg?width=960) Research & Education The Intelligent Inner Lining of Blood Vessels: Nutrients that Support Vascular Health Resveratrol, pterostilbene, anthocyanins, omega-3s, and magnesium may help protect the vascular endothelium from oxidative stress and inflammation. Feb 01, 2024 Read →](https://www.casi.org/articles/intelligent-inner-lining-blood-vessels-nutrients-support-vascular-health)

### [![Exploring the Dual Pathways and Nutrients for Enhanced Nitric Oxide Production](https://www.casi.org/hs-fs/hubfs/casi/featured/2-1-nitric-oxide.jpeg?width=960) Research & Education Exploring the Dual Pathways and Nutrients for Enhanced Nitric Oxide Production Nitric oxide production relies on two distinct pathways, the endogenous and enterosalivary routes, each needing specific nutrient cofactors. Jan 30, 2024 Read →](https://www.casi.org/articles/dual-pathways-nutrients-enhanced-nitric-oxide-production)

### [![Vitamin E Tocotrienols: The Ultimate Cardiometabolic Solution](https://www.casi.org/hs-fs/hubfs/casi/featured/1-25-tocotrienols.jpeg?width=960) Research & Education Vitamin E Tocotrienols: The Ultimate Cardiometabolic Solution Vitamin E tocotrienols from annatto support healthy lipid levels, inflammation, blood pressure, and glucose metabolism, per clinical trials. Jan 25, 2024 Read →](https://www.casi.org/articles/vitamin-e-tocotrienols-cardiometabolic-solution)

### [![Heart Health: The Power of Balanced Electrolytes](https://www.casi.org/hs-fs/hubfs/casi/featured/1-23-heart-health-electrolytes.jpeg?width=960) Research & Education Heart Health: The Power of Balanced Electrolytes Magnesium, sodium, and potassium jointly regulate nerve and muscle function, and their balance supports healthy blood pressure and heart rhythm. Jan 22, 2024 Read →](https://www.casi.org/articles/heart-health-power-of-balanced-electrolytes)

### [![Saunas and Electrolyte Balance: Master These Tools for Ultimate Detox Support](https://www.casi.org/hs-fs/hubfs/casi/featured/1-18-detox-sauna.jpeg?width=960) Research & Education Saunas and Electrolyte Balance: Master These Tools for Ultimate Detox Support Sauna-induced sweating can help excrete heavy metals such as lead and arsenic, but electrolyte and fluid losses need replacing. Jan 18, 2024 Read →](https://www.casi.org/articles/saunas-and-electrolyte-balance-ultimate-detox-support)

### [![The Role of Toxins in Weight Gain](https://www.casi.org/hs-fs/hubfs/casi/featured/1-16-toxins-weight-gain.jpeg?width=960) Research & Education The Role of Toxins in Weight Gain Obesogens, toxins that disrupt lipid metabolism, may contribute to weight gain, and losing 5 to 10 percent of body weight improved cardiometabolic risk. Jan 16, 2024 Read →](https://www.casi.org/articles/role-of-toxins-in-weight-gain)

### [![Acerola Fruit: Promoting Vitamin C Status and Absorption](https://www.casi.org/hs-fs/hubfs/casi/featured/12-28-acerola-fruit.jpeg?width=960) Research & Education Acerola Fruit: Promoting Vitamin C Status and Absorption Acerola's high vitamin C content and polyphenols may enhance vitamin C absorption and retention compared to ascorbic acid supplements. Jan 11, 2024 Read →](https://www.casi.org/articles/acerola-fruit-vitamin-c-status-absorption)

### [![Electrolyte Needs for High-Intensity and Endurance Exercises](https://www.casi.org/hs-fs/hubfs/casi/featured/1-11-electrolyte-needs-exercises.jpeg?width=960) Research & Education Electrolyte Needs for High-Intensity and Endurance Exercises Sodium, potassium, and other electrolytes support hydration during exercise, and evidence shows replacing them, not just water, preserves performance. Jan 11, 2024 Read →](https://www.casi.org/articles/electrolyte-needs-high-intensity-endurance-exercises)

### [![Advanced Ways to Refuel and Maintain Euhydration](https://www.casi.org/hs-fs/hubfs/casi/featured/1-9-euhydration.jpeg?width=960) Research & Education Advanced Ways to Refuel and Maintain Euhydration Euhydration depends on replacing water and electrolytes lost through sweat, with hydration plans individualized to sweat rate and exercise conditions. Jan 09, 2024 Read →](https://www.casi.org/articles/advanced-ways-to-refuel-maintain-euhydration)

### [![Electrolytes: Essential Functions for Optimal Health](https://www.casi.org/hs-fs/hubfs/casi/featured/1-4-electrolytes.jpeg?width=960) Research & Education Electrolytes: Essential Functions for Optimal Health Sodium, potassium, and other electrolytes support hydration, muscle function, bone strength, heart health, and cognitive function. Jan 04, 2024 Read →](https://www.casi.org/articles/electrolytes-essential-functions-optimal-health)

### [![Creating a Holistic Detox Plan for Sustainable Weight Management](https://www.casi.org/hs-fs/hubfs/casi/featured/1-2-holistic-detox_0.jpeg?width=960) Research & Education Creating a Holistic Detox Plan for Sustainable Weight Management A holistic detox plan supports the liver's three detoxification phases with targeted nutrients, fiber, and lifestyle habits for weight management. Jan 03, 2024 Read →](https://www.casi.org/articles/holistic-detox-plan-sustainable-weight-management)

### [![The Biochemistry of Zinc and the Immune Response](https://www.casi.org/hs-fs/hubfs/casi/featured/12-21-zinc-immune.jpeg?width=960) Research & Education The Biochemistry of Zinc and the Immune Response Zinc supports over 300 enzymes and both innate and adaptive immunity, and deficiency is linked to immune dysfunction and autoimmune disease. Dec 21, 2023 Read →](https://www.casi.org/articles/biochemistry-of-zinc-and-the-immune-response)

### [![Polycystic Ovary Syndrome and Chromium Status – Is There a Link?](https://www.casi.org/hs-fs/hubfs/casi/featured/11-23-pcos-chromium.jpeg?width=960) Research & Education Polycystic Ovary Syndrome and Chromium Status – Is There a Link? Chromium picolinate may support glucose and insulin metabolism in women with PCOS, and trials link it to lower BMI, insulin, and testosterone levels. Dec 20, 2023 Read →](https://www.casi.org/articles/polycystic-ovary-syndrome-and-chromium-status)

### [![Herbal Echinacea for Upper Respiratory Tract Health](https://www.casi.org/hs-fs/hubfs/casi/featured/12-14-echinacea-respiratory.jpeg?width=960) Research & Education Herbal Echinacea for Upper Respiratory Tract Health Echinacea's anti-inflammatory compounds may help reduce the risk and shorten the duration of upper respiratory tract infections, clinical trials suggest. Dec 14, 2023 Read →](https://www.casi.org/articles/herbal-echinacea-upper-respiratory-tract-health)

### [![Creatine Monohydrate for Healthy Aging and Brain Function](https://www.casi.org/hs-fs/hubfs/casi/featured/creatine-brain-health.jpeg?width=960) Research & Education Creatine Monohydrate for Healthy Aging and Brain Function Creatine monohydrate raised memory performance in aging adults and shows early evidence for supporting mood, TBI recovery, and brain energy. Dec 12, 2023 Read →](https://www.casi.org/articles/creatine-monohydrate-healthy-aging-brain-function)

### [![New Review Investigates the Modulatory Properties of Vitamin D in Type 2 Diabetic Patients](https://www.casi.org/hs-fs/hubfs/casi/archive/new-study-demonstrates-the-effect-of-vitamin-d-supplementation-on-insulin-sensitivity-and-secretion.jpg?width=960) Science Update New Review Investigates the Modulatory Properties of Vitamin D in Type 2 Diabetic Patients Vitamin D supplementation in type 2 diabetes reduced inflammatory markers and triglycerides while raising HDL, a review of 30 trials found. Dec 08, 2023 Read →](https://www.casi.org/articles/review-investigates-modulatory-properties-vitamin-d-type-2-diabetic-patients)

### [![New Review Investigates the Efficacy of Different Probiotics in IBS](https://www.casi.org/hs-fs/hubfs/casi/featured/11-10-probiotics-ibs_0.jpeg?width=960) Science Update New Review Investigates the Efficacy of Different Probiotics in IBS A network meta-analysis ranked specific probiotic strains and combinations by their effectiveness for IBS symptoms, pain, bloating, and diarrhea. Dec 08, 2023 Read →](https://www.casi.org/articles/efficacy-of-different-probiotics-in-ibs)

### [![The Immune Supportive Properties of Mushrooms](https://www.casi.org/hs-fs/hubfs/casi/featured/12-7-immune-supportive-mushrooms.jpeg?width=960) Research & Education The Immune Supportive Properties of Mushrooms Beta-glucans in mushrooms like shiitake, maitake, reishi, and cordyceps activate immune cells and may support gut microbial balance, studies show. Dec 07, 2023 Read →](https://www.casi.org/articles/immune-supportive-properties-of-mushrooms)

### [![Berberine: For Blood Sugar, Healthy Weight, and Beyond](https://www.casi.org/hs-fs/hubfs/casi/featured/11-14-berberine-hearth-health-blood-sugar.jpeg?width=960) Research & Education Berberine: For Blood Sugar, Healthy Weight, and Beyond Explore the benefits of berberine for heart health, blood sugar management, and weight control, supported by recent research and clinical findings. Dec 05, 2023 Read →](https://www.casi.org/articles/berberine-for-blood-sugar-healthy-weight-and-beyond)

### [![Functional Nutrition Bars: Their Role and Potential Benefits in Supporting Overall Metabolic Health](https://www.casi.org/hs-fs/hubfs/casi/featured/11-16-functional-nutrition-bars.jpeg?width=960) Research & Education Functional Nutrition Bars: Their Role and Potential Benefits in Supporting Overall Metabolic Health Supplemental bars combining protein, fiber, and micronutrients are shown in clinical trials to support glucose control and metabolic health. Nov 30, 2023 Read →](https://www.casi.org/articles/functional-nutrition-bars-role-and-benefits-supporting-metabolic-health)

### [![Unlock the Power of Taurine for Metabolic Health](https://www.casi.org/hs-fs/hubfs/casi/featured/11-30-taurine-metabolic-health.jpeg?width=960) Research & Education Unlock the Power of Taurine for Metabolic Health Taurine, an amino acid found mainly in animal foods, supports glucose and lipid metabolism, and low levels are linked to cardiovascular risk. Nov 30, 2023 Read →](https://www.casi.org/articles/power-of-taurine-for-metabolic-health)

### [![The Latest on Magnesium for Healthy Blood Sugar Support](https://www.casi.org/hs-fs/hubfs/casi/featured/11-9-magnesium-blood-sugar-support.jpeg?width=960) Research & Education The Latest on Magnesium for Healthy Blood Sugar Support Magnesium supports glucose and insulin metabolism, and trials link supplementation to improved A1C, insulin, and HOMA-IR markers in type 2 diabetes. Nov 09, 2023 Read →](https://www.casi.org/articles/latest-on-magnesium-healthy-blood-sugar-support)

### [![Supporting Athletic Performance with MCTs](https://www.casi.org/hs-fs/hubfs/casi/featured/11-7-mcts-athletic-performance.jpeg?width=960) Research & Education Supporting Athletic Performance with MCTs MCTs convert quickly to ketones in the liver and may support athletic performance by preserving glycogen and boosting fat oxidation. Nov 07, 2023 Read →](https://www.casi.org/articles/supporting-athletic-performance-with-mcts)

### [![Zinc Carnosine for Gastric Mucosal Health](https://www.casi.org/hs-fs/hubfs/casi/featured/11-2-zinc-carnosine-gastric.jpeg?width=960) Research & Education Zinc Carnosine for Gastric Mucosal Health Zinc-L-carnosine combines zinc and L-carnosine to support gastric mucosal repair, with trials showing benefits for ulcers and zinc status. Nov 02, 2023 Read →](https://www.casi.org/articles/zinc-carnosine-gastric-mucosal-health)

### [![Collagen: A Clinical Look at Hair and Skin Health](https://www.casi.org/hs-fs/hubfs/casi/featured/10-31-clinical-look-collagen.jpeg?width=960) Research & Education Collagen: A Clinical Look at Hair and Skin Health Hydrolyzed collagen supplementation is linked in trials to better skin hydration, elasticity, and photoaging markers, plus muscle and bone benefits. Oct 31, 2023 Read →](https://www.casi.org/articles/collagen-clinical-look-at-hair-and-skin-health)

### [![Meta-analysis Investigates Efficacy of Vitamin D Supplementation on Bone Health](https://www.casi.org/hs-fs/hubfs/casi/featured/10-27-vit-d-bone-health.jpeg?width=960) Science Update Meta-analysis Investigates Efficacy of Vitamin D Supplementation on Bone Health A meta-analysis of 42 trials found vitamin D lowered bone turnover markers, with the largest gains in older adults and those with liver or kidney disease. Oct 27, 2023 Read →](https://www.casi.org/articles/efficacy-vitamin-d-supplementation-on-bone-health)

### [![L-Glutamine: Promoting Gut Barrier Health](https://www.casi.org/hs-fs/hubfs/casi/featured/10-26-l-glutamine-gut-barrier.jpeg?width=960) Research & Education L-Glutamine: Promoting Gut Barrier Health L-glutamine fuels intestinal cells lining the gut barrier, and trials show it can reduce intestinal permeability in IBS and after intense exercise. Oct 26, 2023 Read →](https://www.casi.org/articles/l-glutamine-promoting-gut-barrier-health)

### [![Unlocking Youthful Skin: Micronutrients for Age-Related Changes](https://www.casi.org/hs-fs/hubfs/casi/featured/10-24-micronutrients-youthful-skin.jpeg?width=960) Research & Education Unlocking Youthful Skin: Micronutrients for Age-Related Changes Arginine silicate and resveratrol support collagen synthesis, and clinical studies show improvements in skin wrinkles and elasticity. Oct 24, 2023 Read →](https://www.casi.org/articles/youthful-skin-micronutrients-age-related-changes)

### [![Meta-Analysis Investigates Relationship Between Depressed Moods and Probiotic Supplementation](https://www.casi.org/hs-fs/hubfs/casi/featured/10-20-depression-probiotics.jpeg?width=960) Science Update Meta-Analysis Investigates Relationship Between Depressed Moods and Probiotic Supplementation A meta-analysis of 13 trials with 776 participants found probiotics improved depression symptoms, with greater effects in adults over 40. Oct 23, 2023 Read →](https://www.casi.org/articles/relationship-between-depressed-moods-probiotic-supplementation)

### [![Vitamin U: Stomach and Gut Support](https://www.casi.org/hs-fs/hubfs/casi/featured/10-19-vitamin-u.jpeg?width=960) Research & Education Vitamin U: Stomach and Gut Support Vitamin U, a methionine derivative found in cabbage juice, has been studied for supporting healing and quality of life in peptic ulcers. Oct 19, 2023 Read →](https://www.casi.org/articles/vitamin-u-stomach-and-gut-support)

### [![Hydroxyapatite for Dental Enamel and Tooth Integrity](https://www.casi.org/hs-fs/hubfs/casi/featured/10-17-hydroxyapatite.jpeg?width=960) Research & Education Hydroxyapatite for Dental Enamel and Tooth Integrity Hydroxyapatite may help remineralize dental enamel, lighten its tone, and ease dentin sensitivity, though larger clinical trials are still needed. Oct 17, 2023 Read →](https://www.casi.org/articles/hydroxyapatite-for-dental-enamel-tooth-integrity)

### [![Review Explores Impact of Phytochemicals and Probiotics on Oxidative Stress](https://www.casi.org/hs-fs/hubfs/casi/featured/10-13-phytochemicals-and-probiotics.jpeg?width=960) Science Update Review Explores Impact of Phytochemicals and Probiotics on Oxidative Stress Resveratrol, quercetin and certain Lactobacillus strains may help the body counter hydrogen peroxide-induced oxidative stress, laboratory studies suggest. Oct 13, 2023 Read →](https://www.casi.org/articles/impact-phytochemicals-and-probiotics-on-oxidative-stress)

### [![Aloe Vera and Bowel Regularity](https://www.casi.org/hs-fs/hubfs/casi/featured/10-12-aloe-vera-bowel-regularity.jpeg?width=960) Research & Education Aloe Vera and Bowel Regularity Barbaloin, a compound in aloe vera, may promote bowel regularity and ease IBS symptoms, though trial results on its benefits remain mixed. Oct 12, 2023 Read →](https://www.casi.org/articles/aloe-vera-and-bowel-regularity)

### [![The Latest on Berberine and Gut Health](https://www.casi.org/hs-fs/hubfs/casi/featured/10-1-berberine-gut-health.jpeg?width=960) Research & Education The Latest on Berberine and Gut Health Berberine may ease intestinal inflammation and support gut microbial diversity, with animal studies showing benefits in colitis and lipid metabolism. Oct 10, 2023 Read →](https://www.casi.org/articles/berberine-and-gut-health)

### [![Systematic Review and Meta-analysis Investigates Potential Link Between Probiotic Use and Orthodontic Health](https://www.casi.org/hs-fs/hubfs/casi/featured/10-6-orthodontic-probiotic.jpeg?width=960) Science Update Systematic Review and Meta-analysis Investigates Potential Link Between Probiotic Use and Orthodontic Health A meta-analysis of 15 trials examines whether probiotics reduce cavity-causing bacteria during orthodontic treatment, though evidence remains inconclusive. Oct 06, 2023 Read →](https://www.casi.org/articles/potential-link-probiotic-use-orthodontic-health)

### [![Histamine Intolerance and Inflammatory Bowel Disease: Any Connection?](https://www.casi.org/hs-fs/hubfs/casi/featured/10-5-histamine-ibd.jpeg?width=960) Research & Education Histamine Intolerance and Inflammatory Bowel Disease: Any Connection? Reduced DAO enzyme activity behind histamine intolerance may worsen gut barrier function, and studies link low DAO levels to inflammatory bowel disease. Oct 05, 2023 Read →](https://www.casi.org/articles/histamine-intolerance-and-inflammatory-bowel-disease)

### [![The Multifaceted Benefits of Lactobacillus Paracasei](https://www.casi.org/hs-fs/hubfs/casi/featured/10-3-lactobacillus-oral-gut.jpeg?width=960) Research & Education The Multifaceted Benefits of Lactobacillus Paracasei Lactobacillus paracasei shows potential to support gut, oral, and kidney health, including reduced diverticular disease symptoms and gum inflammation. Oct 03, 2023 Read →](https://www.casi.org/articles/benefits-of-lactobacillus-paracasei)

### [![Systematic Review and Meta-Analysis Investigates Tocotrienol Supplementation and Blood Sugar Balance](https://www.casi.org/hs-fs/hubfs/casi/featured/9-29-blood-sugar-tocotrienols.jpeg?width=960) Science Update Systematic Review and Meta-Analysis Investigates Tocotrienol Supplementation and Blood Sugar Balance Tocotrienols, a form of vitamin E, may help lower HbA1c in type 2 diabetes, a meta-analysis of ten randomized controlled trials found. Sep 29, 2023 Read →](https://www.casi.org/articles/tocotrienol-supplementation-and-blood-sugar-balance)

### [![Black Cohosh: Promoting Women’s Health and Menopausal Comfort](https://www.casi.org/hs-fs/hubfs/casi/featured/f2467665-c012-47b8-8ee7-ba9f1f24d1e0.jpg?width=960) Research & Education Black Cohosh: Promoting Women’s Health and Menopausal Comfort Black cohosh may ease menopausal hot flashes, sleep disruption, and mood swings, per a meta-analysis of 22 trials in 2,310 women. Sep 28, 2023 Read →](https://www.casi.org/articles/black-cohosh-womens-health-menopausal-comfort)

### [![Can Nicotinamide Riboside Support Age-related Ovarian Health & Cellular Integrity?](https://www.casi.org/hs-fs/hubfs/casi/featured/9-26-nicotinamide-ovarian.jpeg?width=960) Research & Education Can Nicotinamide Riboside Support Age-related Ovarian Health & Cellular Integrity? Nicotinamide riboside may support NAD+ levels and mitochondrial function linked to ovarian aging and reduced NAD+ in polycystic ovary syndrome. Sep 27, 2023 Read →](https://www.casi.org/articles/nicotinamide-riboside-support-age-related-ovarian-health-cellular-integrity)

### [![Review Explores Role of Micronutrients, Antioxidative Status, and Endometrial Health](https://www.casi.org/hs-fs/hubfs/casi/featured/9-22-endometrial-health.jpeg?width=960) Science Update Review Explores Role of Micronutrients, Antioxidative Status, and Endometrial Health Vitamin C, D, and E may reduce pelvic pain and inflammation in endometriosis, while genistein shows similar antioxidative and anti-inflammatory potential. Sep 22, 2023 Read →](https://www.casi.org/articles/role-micronutrients-antioxidative-status-endometrial-health)

### [![DIM to Promote Estrogen Homeostasis](https://www.casi.org/hs-fs/hubfs/casi/featured/9-21-dim-estrogen.jpeg?width=960) Research & Education DIM to Promote Estrogen Homeostasis DIM, a cruciferous vegetable metabolite, may support healthy estrogen metabolism, and early research pairs it with dienogest for endometriosis. Sep 21, 2023 Read →](https://www.casi.org/articles/dim-to-promote-estrogen-homeostasis)

### [![Lifestyle Changes and Micronutrients to Promote Premenstrual Balance](https://www.casi.org/hs-fs/hubfs/casi/featured/9-19-premenstrual-balance.jpeg?width=960) Research & Education Lifestyle Changes and Micronutrients to Promote Premenstrual Balance Aerobic exercise and nutrients like vitamin B6 and fish oil may ease PMS symptoms and support antioxidant status during the menstrual cycle. Sep 19, 2023 Read →](https://www.casi.org/articles/lifestyle-changes-micronutrients-promote-premenstrual-balance)

### [![Recent Systematic Review and Meta-analysis Investigated Relationship Between n-3 PUFA Supplementation and Bone Integrity](https://www.casi.org/hs-fs/hubfs/casi/featured/9-15-bone_integrity.jpeg?width=960) Science Update Recent Systematic Review and Meta-analysis Investigated Relationship Between n-3 PUFA Supplementation and Bone Integrity A meta-analysis of 19 trials found no significant effect of n-3 PUFA supplementation on bone markers, though women showed higher femoral bone density. Sep 15, 2023 Read →](https://www.casi.org/articles/relationship-between-n-3-pufa-supplementation-bone-integrity)

### [![Genistein to Promote Menopausal Comfort and Bone Health](https://www.casi.org/hs-fs/hubfs/casi/featured/9-14-genistein-menopausal.jpeg?width=960) Research & Education Genistein to Promote Menopausal Comfort and Bone Health Genistein, a soy-derived phytoestrogen, may ease hot flashes and support bone density in postmenopausal women, per clinical trial evidence. Sep 14, 2023 Read →](https://www.casi.org/articles/genistein-promote-menopausal-comfort-bone-health)

### [![The Bioactive Properties of Chaste Tree (Vitex)](https://www.casi.org/hs-fs/hubfs/casi/featured/9-12-chaste_tree.jpeg?width=960) Research & Education The Bioactive Properties of Chaste Tree (Vitex) Vitex (chaste tree) supports hormonal balance and menstrual comfort, with one meta-analysis finding a 2.57-fold likelihood of PMS relief over placebo. Sep 12, 2023 Read →](https://www.casi.org/articles/bioactive-properties-of-chaste-tree)

### [![Recent Randomized Controlled Trial Investigates Efficacy of Synbiotics (Prebiotics + Probiotics) on Immune Health](https://www.casi.org/hs-fs/hubfs/casi/featured/9-8-efficacy_of_synbiotics.jpeg?width=960) Science Update Recent Randomized Controlled Trial Investigates Efficacy of Synbiotics (Prebiotics + Probiotics) on Immune Health A synbiotic of FOS, Bifidobacterium, and Lactobacillus lowered CRP and interferon-gamma while raising anti-inflammatory IL-10 in adults. Sep 08, 2023 Read →](https://www.casi.org/articles/efficacy-of-synbiotics-immune-health)

### [![The Postmenopausal Decline of Estrogen and How it May Influence Cardiovascular Health](https://www.casi.org/hs-fs/hubfs/casi/featured/9-7-estrogen-cardiovascular.jpeg?width=960) Research & Education The Postmenopausal Decline of Estrogen and How it May Influence Cardiovascular Health Phytoestrogens, gamma-oryzanol, and taurine may help offset cardiovascular risks tied to postmenopausal estrogen decline, evidence suggests. Sep 07, 2023 Read →](https://www.casi.org/articles/postmenopausal-decline-estrogen-influence-cardiovascular-health)

### [![Clinical Studies Investigate the Role of Micronutrients to Support Menstrual Comfort](https://www.casi.org/hs-fs/hubfs/casi/featured/9-5-minerals_menstrual_comfort.jpeg?width=960) Research & Education Clinical Studies Investigate the Role of Micronutrients to Support Menstrual Comfort Zinc reduced menstrual pain in a trial of teens with dysmenorrhea, while calcium, vitamin D, and selenium showed benefits for women with PCOS. Sep 05, 2023 Read →](https://www.casi.org/articles/clinical-studies-micronutrients-support-menstrual-comfort)

### [![Recent Pilot Study Investigates Inositol’s Potential to Support Endometrial Health](https://www.casi.org/hs-fs/hubfs/casi/featured/9-1-inositol-endometrial.jpeg?width=960) Science Update Recent Pilot Study Investigates Inositol’s Potential to Support Endometrial Health D-chiro-inositol supplementation improved endometrial thickness, menstrual length, and heavy bleeding days in a small pilot study of perimenopausal women. Sep 01, 2023 Read →](https://www.casi.org/articles/study-investigates-inositol-potential-support-endometrial-health)

### [![The Association Between Stress and Hot Flashes](https://www.casi.org/hs-fs/hubfs/casi/featured/8-31-stress-hotflashes.jpeg?width=960) Research & Education The Association Between Stress and Hot Flashes Perceived stress and anxiety are linked to more frequent and severe menopausal hot flashes, and compounds like gamma-oryzanol and taurine may ease them. Aug 31, 2023 Read →](https://www.casi.org/articles/association-between-stress-and-hot-flashes)

### [![Vaginal Dysbiosis and the Supportive Role of Probiotics](https://www.casi.org/hs-fs/hubfs/casi/featured/8-29-vaginal-dysbiosis.jpeg?width=960) Research & Education Vaginal Dysbiosis and the Supportive Role of Probiotics Lactobacillus strains help maintain vaginal pH and microbial balance, and probiotic supplementation may support recovery from bacterial vaginosis. Aug 29, 2023 Read →](https://www.casi.org/articles/vaginal-dysbiosis-supportive-role-probiotics)

### [![Recent Review Explores Relationship Between Berberine and the Gut Microbiome](https://www.casi.org/hs-fs/hubfs/casi/archive/nn_2.jpg?width=960) Science Update Recent Review Explores Relationship Between Berberine and the Gut Microbiome Explore how berberine supports gut health, blood sugar management, and lipid metabolism, revealing its potential benefits for overall wellness and aging. Aug 25, 2023 Read →](https://www.casi.org/articles/relationship-between-berberine-gut-microbiome)

### [![Taurine: Promoting Healthy Aging and Menopausal Comfort](https://www.casi.org/hs-fs/hubfs/casi/featured/8-24-taurine.jpeg?width=960) Research & Education Taurine: Promoting Healthy Aging and Menopausal Comfort Taurine, an amino acid abundant in muscle and brain tissue, may support menopausal comfort and healthy aging through metabolic and cardiovascular effects. Aug 24, 2023 Read →](https://www.casi.org/articles/taurine-healthy-aging-and-menopausal-comfort)

### [![The Potential Link Between CoQ10 and Endocrine Health](https://www.casi.org/hs-fs/hubfs/casi/featured/8-22-coq10-endocrine.jpeg?width=960) Research & Education The Potential Link Between CoQ10 and Endocrine Health Coenzyme Q10 supports mitochondrial and thyroid function, and research links it to improvements in glucose metabolism, PCOS, and fertility. Aug 22, 2023 Read →](https://www.casi.org/articles/link-between-coq10-endocrine-health)

### [![Recent Systematic Review Investigates Relationship Between Selenium Supplementation and Ovarian Health](https://www.casi.org/hs-fs/hubfs/casi/archive/adobestock_209517331.jpg?width=960) Science Update Recent Systematic Review Investigates Relationship Between Selenium Supplementation and Ovarian Health Explore how selenium supplementation may enhance ovarian health and support metabolic balance in individuals with PCOS… Aug 18, 2023 Read →](https://www.casi.org/articles/selenium-supplementation-ovarian-health)

### [![Phytoestrogens to Help Diminish Mild Hot Flashes](https://www.casi.org/hs-fs/hubfs/casi/featured/8-17-phytoestrogens.jpeg?width=960) Research & Education Phytoestrogens to Help Diminish Mild Hot Flashes Phytoestrogens such as genistein and spruce lignans may support estrogen balance and reduce the frequency and severity of menopausal hot flashes. Aug 17, 2023 Read →](https://www.casi.org/articles/phytoestrogens-to-help-diminish-hot-flashes)

### [![Supporting the Vaginal Microbiome: The Why and How](https://www.casi.org/hs-fs/hubfs/casi/featured/8-15-vaginal-microbiome.jpeg?width=960) Research & Education Supporting the Vaginal Microbiome: The Why and How Certain Lactobacillus strains may support vaginal microbial balance and reduce bacterial vaginosis, according to several clinical studies. Aug 15, 2023 Read →](https://www.casi.org/articles/supporting-the-vaginal-microbiome)

### [![Recent Meta-analysis Investigates Role of Quercetin in Post-Exercise Recovery](https://www.casi.org/hs-fs/hubfs/casi/featured/8-11-quercetin.jpeg?width=960) Science Update Recent Meta-analysis Investigates Role of Quercetin in Post-Exercise Recovery Quercetin, a flavonoid in onions and berries, may reduce exercise-induced muscle damage and support antioxidant status, per a recent meta-analysis. Aug 14, 2023 Read →](https://www.casi.org/articles/recent-meta-analysis-quercetin-post-exercise-recovery)

### [![Resveratrol and Curcumin to Promote Mitochondrial Biogenesis](https://www.casi.org/hs-fs/hubfs/casi/featured/adobestock_182164911.jpeg?width=960) Research & Education Resveratrol and Curcumin to Promote Mitochondrial Biogenesis Resveratrol and curcumin, polyphenols with antioxidant properties, may promote mitochondrial biogenesis to support cellular energy production. Aug 10, 2023 Read →](https://www.casi.org/articles/resveratrol-curcumin-promote-mitochondrial-biogenesis)

### [![The Latest on Nicotinamide Riboside for Optimal Energy and Cellular Health](https://www.casi.org/hs-fs/hubfs/casi/featured/8-8-nicotinamide_riboside.jpeg?width=960) Research & Education The Latest on Nicotinamide Riboside for Optimal Energy and Cellular Health Nicotinamide riboside raises NAD+ levels and may support mitochondrial function, cellular energy production, and healthy aging, research suggests. Aug 08, 2023 Read →](https://www.casi.org/articles/nicotinamide-riboside-optimal-energy-and-cellular-health)

### [![Recent Review Explores Relationship Between Eye Health and Nutrients to Support Antioxidative Status](https://www.casi.org/hs-fs/hubfs/casi/featured/adobestock_517016413.jpeg?width=960) Science Update Recent Review Explores Relationship Between Eye Health and Nutrients to Support Antioxidative Status Zinc, alpha-lipoic acid, riboflavin, and resveratrol may support the eye's antioxidant defenses against blue light and age-related stress. Aug 07, 2023 Read →](https://www.casi.org/articles/recent-review-eye-health-nutrients-antioxidative-status)

### [![Rhodiola’s Impact on Cellular Energy Production and Mitochondrial Function](https://www.casi.org/hs-fs/hubfs/casi/featured/adobestock_138294923.jpeg?width=960) Research & Education Rhodiola’s Impact on Cellular Energy Production and Mitochondrial Function Rhodiola rosea supports mitochondrial energy production and stress resilience; a trial found 50 mg daily eased fatigue and improved student performance. Aug 07, 2023 Read →](https://www.casi.org/articles/rhodiola-cellular-energy-production-mitochondrial-function)

### [![S-Acetyl Glutathione to Support Mitochondrial Health](https://www.casi.org/hs-fs/hubfs/casi/featured/adobestock_605584038_0.jpeg?width=960) Research & Education S-Acetyl Glutathione to Support Mitochondrial Health S-acetyl glutathione (SAG) may replenish intracellular glutathione more effectively than GSH, per lab studies on viral and liver cell models. Aug 07, 2023 Read →](https://www.casi.org/articles/s-acetyl-glutathione-support-mitochondrial-health)

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