---
title: Evidence-based Wellness Education | Science Update
description: Science Update | Evidence-based nutrition science, peer-reviewed and free for everyone. An educational publication of Designs for Health.
---

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Science Update

# Science Update

 The latest evidence-based reporting in Science Update.

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## Articles

### [![A Case Series on an Allulose-Containing Gummy in Healthy Adults Monitored by Continuous Glucose Monitoring](https://www.casi.org/hs-fs/hubfs/Sept-CASI-Allulose%20%281%29.jpeg?width=960) Science Update A Case Series on an Allulose-Containing Gummy in Healthy Adults Monitored by Continuous Glucose Monitoring Explore a CGM-monitored case series on how an allulose gummy may help reduce postprandial glucose spikes and glycemic variability in healthy adults. Sep 09, 2026 Read →](https://www.casi.org/articles/a-case-series-on-an-allulose-containing-gummy-in-healthy-adults-monitored-by-continuous-glucose-monitoring)

### [![A Case Report on Vitamin C Supplementation in a 67-Year-Old Male with Leukopenia](https://www.casi.org/hs-fs/hubfs/July-21_Leukopenia-vita-c_460547506.jpeg?width=960) Science Update A Case Report on Vitamin C Supplementation in a 67-Year-Old Male with Leukopenia Explore a case report on oral vitamin C supplementation and changes in white blood cell and neutrophil counts in a 67-year-old man with chronic leukopenia. Jul 21, 2026 Read →](https://www.casi.org/articles/a-case-report-on-vitamin-c-supplementation-in-a-67-year-old-male-with-leukopenia)

### [![A Clinical Trial on Geranylgeraniol Supplementation for Testosterone Support in Middle-Aged Adults](https://www.casi.org/hs-fs/hubfs/casi/archive/june16-gg-testosterone.jpg?width=960) Science Update A Clinical Trial on Geranylgeraniol Supplementation for Testosterone Support in Middle-Aged Adults Geranylgeraniol did not raise testosterone overall, but a trial found men with lower baseline levels saw about a 28 ng/dL increase after supplementation. Jun 17, 2026 Read →](https://www.casi.org/articles/geranylgeraniol-supplementation-testosterone-support)

### [![A Case Report on a Functional GI Testing Protocol in a 35-Year-Old Female with Gastrointestinal and Joint Discomfort](https://www.casi.org/hs-fs/hubfs/May-7-Functional-GI-Testing-35-Yr-Old.jpeg?width=960) Science Update A Case Report on a Functional GI Testing Protocol in a 35-Year-Old Female with Gastrointestinal and Joint Discomfort Explore how functional GI testing and comprehensive stool analysis guided a personalized protocol for gastrointestinal symptoms and joint discomfort. May 07, 2026 Read →](https://www.casi.org/articles/a-case-report-on-a-functional-gi-testing-protocol-in-a-35-year-old-female-with-gastrointestinal-and-joint-discomfort)

### [![Integrative Management of Estrogen Dominance, Methylation Impairment, and Histamine Intolerance in Perimenopause: A Case Report](https://www.casi.org/hs-fs/hubfs/April-23-Integrative-Management-Estrogen.jpeg?width=960) Science Update Integrative Management of Estrogen Dominance, Methylation Impairment, and Histamine Intolerance in Perimenopause: A Case Report Explore a case report on estrogen dominance in perimenopause, impaired methylation, histamine intolerance, and a personalized integrative health care plan. Apr 23, 2026 Read →](https://www.casi.org/articles/integrative-management-of-estrogen-dominance-methylation-impairment-and-histamine-intolerance-in-perimenopause-a-case-report)

### [![Bifidobacterium Postbiotic Promotes Healthy Body Composition and Akkermansia Genus: A Randomized Controlled Trial](https://www.casi.org/hs-fs/hubfs/Bifidobacterium%20Postbiotic%20Promotes%20Healthy%20Body%20Composition%20and%20Akkermansia.png?width=960) Science Update Bifidobacterium Postbiotic Promotes Healthy Body Composition and Akkermansia Genus: A Randomized Controlled Trial A randomized controlled trial explores how a Bifidobacterium postbiotic improves visceral fat, insulin resistance… Apr 14, 2026 Read →](https://www.casi.org/articles/bifidobacterium-postbiotic-promotes-healthy-body-composition-and-akkermansia-genus-a-randomized-controlled-trial)

### [![A Case Report on Anaerostipes caccae Supplementation in a 47-Year-Old Female with Long-Term Food Intolerances](https://www.casi.org/hs-fs/hubfs/April-9-Anaerostipes-47-yo-Woman.jpeg?width=960) Science Update A Case Report on Anaerostipes caccae Supplementation in a 47-Year-Old Female with Long-Term Food Intolerances Explore one case report on Anaerostipes caccae, a butyrate-producing probiotic, gut microbiome changes, digestive comfort, and long-term food intolerances. Apr 09, 2026 Read →](https://www.casi.org/articles/a-case-report-on-anaerostipes-caccae-supplementation-in-a-47-year-old-female-with-long-term-food-intolerances)

### [![A Case Report on DIM Supplementation in a 78-Year-Old Male with Elevated Prostate-Specific Antigen (PSA)](https://www.casi.org/hs-fs/hubfs/March-24-DIM-Supplementation.jpeg?width=960) Science Update A Case Report on DIM Supplementation in a 78-Year-Old Male with Elevated Prostate-Specific Antigen (PSA) DIM supplementation and stopping a cholesterol supplement were linked to a sharp PSA drop and rising testosterone in a 78-year-old man's case report. Mar 30, 2026 Read →](https://www.casi.org/articles/dim-supplementation-prostate-specific-antigen)

### [![A Case Report on a Homocysteine-Supporting Nutraceutical in Seven Patients with Elevated Homocysteine](https://www.casi.org/hs-fs/hubfs/casi/featured/march-19-homocysteine.jpeg?width=960) Science Update A Case Report on a Homocysteine-Supporting Nutraceutical in Seven Patients with Elevated Homocysteine A homocysteine-targeted nutraceutical with B vitamins and TMG lowered homocysteine in seven patients, with reductions from 9.4% to 46.4%. Mar 23, 2026 Read →](https://www.casi.org/articles/homocysteine-supporting-nutraceutical)

### [![A Case Report on Nutraceutical Support and Urinary Metabolite Testing on a 61-Year-Old Woman with Menopausal Challenges](https://www.casi.org/hs-fs/hubfs/casi/featured/feb-26-nutraceutical-support-menopausal-challenges.jpeg?width=960) Science Update A Case Report on Nutraceutical Support and Urinary Metabolite Testing on a 61-Year-Old Woman with Menopausal Challenges A 61-year-old postmenopausal woman's urine hormone testing guided a nutraceutical and diet protocol that raised metabolites and eased hot flashes. Feb 27, 2026 Read →](https://www.casi.org/articles/nutraceutical-support-urinary-metabolite-testing)

### [![A Case Report on a Personalized Nutraceutical, Dietary, Lifestyle Protocol Supporting an 11-Year-Old Boy with Crohn’s Disease](https://www.casi.org/hs-fs/hubfs/casi/featured/feb-19-11-yr-old-boy-crohns.jpeg?width=960) Science Update A Case Report on a Personalized Nutraceutical, Dietary, Lifestyle Protocol Supporting an 11-Year-Old Boy with Crohn’s Disease A personalized nutraceutical and dietary protocol in an 11-year-old with Crohn's disease resolved symptoms and normalized fecal calprotectin. Feb 19, 2026 Read →](https://www.casi.org/articles/case-report-protocol-crohns-disease)

‹ 1 [2](https://www.casi.org/articles/tag/science-update/page/2) [›](https://www.casi.org/articles/tag/science-update/page/2)

Most read this month

1. 01
   
   [Taurine and Glycine: The Benefits of Combining These Two Amino Acids](https://www.casi.org/articles/taurine-and-glycine-benefits-combining-amino-acids)
   
   Research & Education
2. 02
   
   [Magnesium Glycinate Chelate Buffered: A Smart Approach to Magnesium Supplementation](https://www.casi.org/articles/magnesium-glycinate-chelate-buffered-a-smart-approach-to-magnesium-supplementation)
   
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3. 03
   
   [Ubiquinone vs. Ubiquinol: Does the Form of CoQ10 Matter – Or Is Delivery the Real Key?](https://www.casi.org/articles/ubiquinone-ubiquinol-coq10-delivery)
   
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4. 04
   
   [B Vitamins 101: Functions, Food Sources, and Daily Requirements](https://www.casi.org/articles/b-vitamins-101-functions-food-sources-and-daily-requirements)
   
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5. 05
   
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