CASI Blog
Peer-reviewed nutrition science, organized by topic and section.
Fully-referenced deep dives, written for practitioners and the science-curious.
Amino Acids
Creatine is endogenously formed from the amino acids arginine, glycine, and methionine, and is involved in muscular contraction; approximately 95% is stored in skeletal muscle, particularly type 2 fibers. Two-thirds of intramuscular creatine is phosphocreatine (PCr) and the remaining one-third is fr
Science Update
Insulin resistance is often preventable and reversible through lifestyle changes, proper nutrition, supplements, exercise and stress management. Weight loss and exercise are the best treatments for restoring the body's ability to respond to insulin.
Science Update
Irritable bowel syndrome (IBS) can be debilitating, causing cramping, abdominal pain, bloating, gas, diarrhea, and constipation. IBS can affect one’s work, sleep, and relationships.
Immune Support
The oldest recorded medicinal use of mushrooms dates back to around the 1st century BC. Historical records throughout the centuries have shown that mushrooms are a subject of interest to support overall health. Mushrooms provide nutritional value (as a good source of selenium, potassium, riboflavin,
Blood Sugar Management
Explore the benefits of berberine for heart health, blood sugar management, and weight control, supported by recent research and clinical findings.
Immune Support
Functional nutrition bars are supplemental bars that provide essential nutrients and potentially offer clinical benefits to various bodily systems. They may promote bone, joint, skin, gut, nail, and immune health and may support athletic performance. Beyond their convenient delivery format and delic
Amino Acids
Taurine is a conditionally essential amino acid that supports overall metabolic health. As the endogenous synthesis of taurine can be relatively low, dietary intake is the primary way to maintain healthy taurine status. However, taurine only occurs naturally in animal-based foods like dairy, eggs, m
Cellular Energy
Magnesium is an essential mineral that serves as an enzyme cofactor for more than 600 reactions in the body, including harnessing energy from carbohydrates. Unfortunately, magnesium (Mg) insufficiency is common in the United States due to the widespread use of demineralized water and soil and the in
Cellular Energy
Medium-chain triglycerides (MCTs) are a type of molecule, often derived from coconut oil, that may help promote optimal cellular energy and athletic performance through the unique way they are metabolized in the body. MCTs are digested and absorbed differently than other fats. They are more readily
Research & Education
Zinc-L-carnosine (ZnC) is a chelated compound containing the dipeptide L-carnosine and the essential trace element zinc. Human trials and animal studies have demonstrated the ability of ZnC to promote gastrointestinal (GI) mucosal barrier function through its demonstrated anti-inflammatory and antio
Nutrition Notes
The skin is composed of three layers: epidermis, dermis, and hypodermis. The dermis is the largest of the three skin layers and contains a high amount of collagen. During the aging process or exposure to certain environmental factors including UV light, the skin’s collagen structure may degrade or a