Science Update
Is niacin safe?
Niacin has decades of safe use, and recent safety concerns trace mainly to a flushing-blocking drug combined with it, not niacin itself.
CASI Blog
Peer-reviewed nutrition science, organized by topic and section.
Fully-referenced deep dives, written for practitioners and the science-curious.
Science Update
Niacin has decades of safe use, and recent safety concerns trace mainly to a flushing-blocking drug combined with it, not niacin itself.
Memory Support
Medium-chain triglycerides raise ketone levels that fuel the brain, with trials linking them to improved memory and cognition in Alzheimer's and MCI.
Dermatological Health
Selenium supplementation raised glutathione peroxidase activity in one study, supporting its role in easing oxidative stress linked to acne vulgaris.
Sleep Quality
Acid reflux symptoms often stem from too little stomach acid rather than too much, with betaine HCL and other natural approaches offering support.
Ginger Family
Curcumin, turmeric's key polyphenol, shows early evidence for prenatal safety, contraception, endothelial function, and endometriosis treatment.
Science Update
Lean beef intake at higher levels helped lower blood pressure in a study testing total protein intake within a DASH-like diet pattern.
Cellular Health
DIM, a cruciferous vegetable metabolite known for balancing estrogen, shows early evidence of inducing cancer cell apoptosis and slowing tumor growth.
Research & Education
Common fats like lard and coconut oil are complex mixtures, with lard containing more monounsaturated than saturated fat despite its reputation.
Science Update
Gut T cells regulate IgA production to shape which bacterial populations the immune system tolerates, tying dysbiosis directly to immune-related disorders.
Research & Education
Paleo diet approaches vary widely, from strict grain-free plans to a broader ancestral health paradigm that reintroduces select traditional foods.
Science Update
The human gut converts natural folates to 5-MTHF efficiently but has limited capacity to convert folic acid, which may leave it unmetabolized.