Metabolic Health
Normal Weight Obesity: Looks Can Be Deceiving
Normal weight obesity, or being thin outside but metabolically unhealthy inside, shows that normal BMI can mask insulin resistance and inflammation.
CASI Blog
Peer-reviewed nutrition science, organized by topic and section.
Fully-referenced deep dives, written for practitioners and the science-curious.
Metabolic Health
Normal weight obesity, or being thin outside but metabolically unhealthy inside, shows that normal BMI can mask insulin resistance and inflammation.
Science Update
Bacteria that cause gum disease may also promote heart disease, as a mouse study found their spread raised cholesterol and inflammation markers.
Science Update
Children with autism spectrum disorder show altered gut bacteria and neurotransmitter metabolites, pointing to a gut-brain link in ASD.
PBMKID
Children with autism spectrum disorder show altered gut bacteria and stool metabolites linked to dopamine breakdown and glutamate-GABA balance.
Cellular Energy
Green tea catechins, adequate sleep, mitochondrial cofactors, and omega-3s each support metabolic rate, insulin sensitivity, and fat oxidation.
Research & Education
Carnitine supports mitochondrial energy production and may offer a steadier alternative to caffeine for sustained energy, especially in low-meat diets.
Science Update
Glucosamine extended lifespan in aging mice and improved glucose metabolism, apparently by mimicking the metabolic effects of a low-carbohydrate diet.
Delving Deeper Hypertension
RBC mineral levels, heavy metal exposure, and CoQ10 status offer a fuller picture of hypertension than routine blood pressure checks alone.
Research & Education
Garlic's organosulfur compounds, especially the stable metabolite ajoene, show antimicrobial and immune-boosting activity in research on its bioactives.
Science Update
As high-school concussion rates rise, research points to GPC, a choline compound, for protecting brain cells and easing post-concussion symptoms.
Cellular Health
High-protein diets do not appear to harm healthy kidneys, and evidence linking meat protein to cancer risk remains mixed and mechanism-dependent.