CASI Blog
Peer-reviewed nutrition science, organized by topic and section.
Fully-referenced deep dives, written for practitioners and the science-curious.
Explore a case report on estrogen dominance in perimenopause, impaired methylation, histamine intolerance, and a personalized integrative health care plan.
Metabolic Health
A randomized controlled trial explores how a Bifidobacterium postbiotic improves visceral fat, insulin resistance, and Akkermansia abundance in adults with abdominal obesity.
Explore one case report on Anaerostipes caccae, a butyrate-producing probiotic, gut microbiome changes, digestive comfort, and long-term food intolerances.
Nutrition Notes
Prostate-specific antigen (PSA) is a widely used biomarker for evaluating prostate health, often associated with conditions such as benign prostatic hyperplasia (BPH) and prostate cancer. PSA is not, however, a direct measure of disease, but rather a clinical marker influenced by underlying prostate
Science Update
Homocysteine (Hcy) is a sulfur‑containing amino acid formed during methionine metabolism and plays an important role in the body’s methylation cycle. Although it is a normal metabolic intermediate, elevated circulating levels have been associated with increased risk of cardiovascular disease, neurol
Cellular Energy
Coenzyme Q10 (CoQ10) is a naturally occurring, lipid-soluble compound synthesized by the body that has been extensively studied for its role in supporting cardiovascular health, mitochondrial energy production, and healthy aging. Despite the large body of research on CoQ10, an important question co
Nutrition Notes
Stress is a common and unavoidable component of modern life. It may arise from a variety of sources, including work demands, social pressures, and environmental challenges. While short-term stress can be beneficial in certain situations, such as helping sharpen attention and enhance performance, per
Glucose Metabolism
Excess intake of added sugars is strongly associated with obesity, insulin resistance, and type 2 diabetes (T2D), making dietary sugar reduction a central target of metabolic health interventions. While low-calorie sweeteners can reduce energy intake, many do not meaningfully influence postprandial
Science Update
Menopause is a natural biological process that affects an estimated 1.3 million women in the US every year. Defined as twelve consecutive months without a menstrual period, menopause typically occurs in a woman’s early 50s and marks the end of reproductive capacity. While often an overlooked area in
Immune Support
A growing body of research shows that sleep health is far more complex than a single hormone. Sleep is not governed solely by the brain, but by a quiet highway of signals running between the gastrointestinal tract and the central nervous system. This bidirectional highway is the gut–brain axis. This
Science Update
Crohn’s disease (CD) is a chronic inflammatory bowel disease that can affect any region of the gastrointestinal tract, most commonly the terminal ileum and colon. In pediatric populations, the disease often presents more severely, with symptoms including abdominal pain, diarrhea, fatigue, bloating,