CASI Blog
Peer-reviewed nutrition science, organized by topic and section.
Fully-referenced deep dives, written for practitioners and the science-curious.
Nutrition Notes
Americans consume approximately 286 more calories per day than in 1977-1978. Today, Americans consume less potatoes, beef, eggs, milk, ice cream, and margarine, and more chicken, cooking oils, corn products, cheese, rice, and yogurt. Despite this increase in total calories consumed, Americans are fa
Science Update
The skeletal muscle is the largest metabolic organ in the human body and plays an important role in metabolic health and overall well-being. It is also regarded as an endocrine and paracrine organ, where muscle-derived signaling proteins, called myokines, facilitate communication between the muscles
Science Update
A hallmark of health is the ability to maintain homeostasis over time, which includes the ability to repair and regenerate cells and tissues when necessary. After intense physical activity and resistance training, muscle damage may occur, which is characterized by delayed onset muscle soreness, or D
Immune Support
What are immunoglobulins?
Immune Support
The lumen of the gastrointestinal tract is lined with a mucus layer produced primarily by specialized epithelial cells called goblet cells. This mucus layer plays a crucial role in maintaining gut health and function. It also hosts various gut microbiota species, immune system cells, and mucus compo
Nutrition Notes
The gastrointestinal tract of humans requires many nutrients and other health-supportive compounds to function at its best. Much like a symphony requiring multiple instrument sections to play harmoniously, the GI tract needs support from foods, fiber, bacteria, and various metabolites to promote hea
Research & Education
What is the 5R program?
Immune Support
N-acetyl-D-glucosamine (NAG or GlcNAC) is an amino sugar derived from glucosamine, which is naturally produced by the body to maintain optimal health in various ways. First and foremost, NAG plays a pivotal role in promoting balanced immune function through the process of O-GlcNAcylation, a type of
Research & Education
Digestive enzymes are critical for breaking down food into nutrients that the body can absorb and utilize, transforming the saying "You are what you eat" into the more accurate "You are what you can absorb and digest." These enzymes, produced naturally by the body or supplemented as needed, are esse
Research & Education
The 5R Blueprint for Gut Health
Sleep Quality
The skin is the body’s largest organ and undergoes many changes during aging. The skin is subject to aging due to internal factors and external factors. Internal factors may include the body’s nutrient and antioxidant status. External factors, like environmental conditions (for example, wind, sun ex